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Litchi, a prominent species within the genus of the Sapindaceae family, is a fruit renowned for its significant nutritional, health, and pharmacological properties. Polysaccharides are one of the functional active ingredients in litchi, with various biological functions such as hypoglycemic effect, prebiotic effect, promoting effect on exopolysaccharide production by , antioxidant effect, antiproliferative effect, immunoregulatory effect. Consequently, research on litchi polysaccharides has steadily expanded and deepened in recent years. A comprehensive review of existing studies is essential for advancing the understanding of these polysaccharides. This article provides an overview of the current state of research on litchi polysaccharides, covering various aspects such as extraction, purification, chemical structure, health benefits, and structure-activity relationships. Furthermore, it offers valuable insights to guide the continued development of litchi polysaccharides, establishing a scientific foundation for their more efficient and rational utilization.
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http://dx.doi.org/10.3389/fphar.2025.1618885 | DOI Listing |
Front Pharmacol
August 2025
Heilongjiang University of Chinese Medicine, Key Laboratory of Basic and Application Research of Beiyao, Ministry of Education, Harbin, China.
Litchi, a prominent species within the genus of the Sapindaceae family, is a fruit renowned for its significant nutritional, health, and pharmacological properties. Polysaccharides are one of the functional active ingredients in litchi, with various biological functions such as hypoglycemic effect, prebiotic effect, promoting effect on exopolysaccharide production by , antioxidant effect, antiproliferative effect, immunoregulatory effect. Consequently, research on litchi polysaccharides has steadily expanded and deepened in recent years.
View Article and Find Full Text PDFJ Nutr Sci Vitaminol (Tokyo)
August 2025
Faculty of Medical Informatics, Hokkaido Information University.
Obesity is known to induce diabetes, hypertension, and dyslipidemia, and reducing obesity is important from the perspective of disease prevention. Oligonol, a standardized oligomerized-polyphenol from Litchi chinensis fruit extract, is expected to have high absorption and body fat reduction. In this study, the effects of Oligonol intake on abdominal fat were examined in overweight Japanese participants.
View Article and Find Full Text PDFFood Chem
August 2025
College of Pharmaceutical Sciences, Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China. Electronic address:
Litchi chinensis Sonn. (litchi) pericarp, a major byproduct of litchi processing, is rich in bioactive polysaccharides; however, the structure-bioactivity relationship has not been well studied. Here, a homogenous polysaccharide LPPs-1 was isolated and purified from litchi pericarp, having a weight-average molecular weight of 38.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China. Electronic address:
The poor mechanical strength and singular therapeutic function of conventional hydrogel dressings have significantly constrained their clinical applicability for treating infected wounds. Consequently, the development of intelligent non-antibiotic dressings that exhibit both high mechanical strength and multiple synergistic therapeutic mechanisms represents a significant challenge. To address this, a "double polymerity-wide crosslinking" strategy was proposed in this work.
View Article and Find Full Text PDFJ Agric Food Chem
August 2025
Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510642, China.
Plant-derived pectic polysaccharides and epigallocatechin gallate (EGCG) extensively interact during processing and consumption. Both compounds are known to regulate host immunity, yet their respective roles and combined effects in the microbiota-metabolic-immune axis remain unclear. This study investigated the effects of litchi-derived pectic polysaccharides (SCLP) and EGCG in cyclophosphamide-induced immunocompromised and intestinal barrier-damaged mice.
View Article and Find Full Text PDF