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Industry 4.0 is driving innovation in cosmetics, with artificial intelligence (AI) playing a transformative role in modeling, prediction, and product design. This review explores the integration and current advances in emulsified cosmetic product design from a multiscale approach at molecular, microscopic, and macroscopic stages. Therefore, AI applications ranging from interfacial tension estimation to droplet size distribution modeling, cosmetic selection for skin suitability, and packaging design are discussed and explored to review the opportunity of encompassing methodologies at the design stage of an emulsified cosmetic. As a result, this review identifies challenges and opportunities, emphasizing the transformative potential of AI integration in the cosmetics field, focusing on the opportunity to reduce experimental time and incorporate consumer-relevant formulations aiming to revolutionize the field.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12392008 | PMC |
http://dx.doi.org/10.1021/acsomega.5c03316 | DOI Listing |
Haematologica
September 2025
Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD,.
Immunotherapies, including cell therapies, are effective anti-cancer agents. However, cellular product persistence can be limiting with short functional duration of activity contributing to disease relapse. A variety of manufacturing protocols are used to generate therapeutic engineered T-cells; these differ in techniques used for T-cell isolation, activation, genetic modification, and other methodology.
View Article and Find Full Text PDFStroke
September 2025
Department of Neurology, Yale School of Medicine, New Haven, CT (L.H.S.).
Preclinical stroke research faces a critical translational gap, with animal studies failing to reliably predict clinical efficacy. To address this, the field is moving toward rigorous, multicenter preclinical randomized controlled trials (mpRCTs) that mimic phase 3 clinical trials in several key components. This collective statement, derived from experts involved in mpRCTs, outlines considerations for designing and executing such trials.
View Article and Find Full Text PDFPhys Chem Chem Phys
September 2025
School of Electrical and Automation Engineering, Suzhou University of Technology, Suzhou, 215506, China.
A flexible bipolarization conversion metasurface based on graphene is proposed in this paper, which can achieve single-band linear-to-linear (LTL) and dual-band linear-to-circular (LTC) polarization conversion. The polarization conversion ratio (PCR) and axial ratio (AR) are dynamically regulated by varying the sheet resistance () of graphene. When = 1400 Ω Sq, the designed metasurface achieves a single-band LTL polarization conversion of 7.
View Article and Find Full Text PDFPhys Chem Chem Phys
September 2025
Key Laboratory for Photonic and Electronic Bandgap Materials, Ministry of Education, School of Physics and Electronic Engineering, Harbin Normal University, Harbin 150025, China.
Transition metal dichalcogenides (TMDs) have been extensively studied as efficient photocatalysts for water splitting. However, the utilization efficiency of photogenerated carriers remains a major limitation for their practical applications. An effective approach to address this issue is the construction of Z-scheme heterostructures.
View Article and Find Full Text PDFJ Mater Chem B
September 2025
State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, School of Materials Science and Engineering, South China University of Technology, Guangzhou, 510640, China.
Mitochondria-targeted photodynamic therapy (PDT) circumvents the short lifetime and action radius limitation of reactive oxygen species (ROS) and greatly improves the anticancer PDT efficacy. However, current approaches require different molecular engineering strategies to separately improve ROS production and introduce mitochondria targeting ability, which involve tedious synthetic procedures. Herein, we report a facile one-step cationization strategy that simultaneously improves the ROS generation efficiency and introduces mitochondria targeting ability for enhanced PDT.
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