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Goals: To assess esophageal cancer (EC) burdens among older adults aged 60+ from 1990 to 2021.
Background: With the aging global population, EC in elderly presents a significant health challenge.
Study: 2021 Global Burden of Disease (GBD) data were used to calculate age-standardized rates (ASRs) for incidence, prevalence, mortality, and disability-adjusted life years (DALYs). Joinpoint regression was used to calculate the average annual percentage change (AAPC) to assess temporal trends. Pearson's correlation analysis investigated the relationship between socio-demographic index (SDI) and the male-to-female ratios of ASRs.
Results: In 2021, there were 421,336 incident cases, 655,313 prevalent cases, 410,902 deaths, and 8,059,156 DALYs due to EC in older adults globally, doubling since 1990. The age-standardized incidence rate, age-standardized mortality rate, and age-standardized DALYs rate exhibited decline from 1990 to 2021, with respective AAPCs of -0.62 (95% CI: -0.76 to -0.48), -0.9 (95% CI: -1.05 to -0.75), and -1.11 (95% CI: -1.25 to -0.97), while age-standardized prevalence rate (AAPC: -0.04, 95% CI: -0.16 to 0.09) remained stable. Western Sub-Saharan Africa experienced the steepest rise in ASRs from 1990 to 2021, while East Asia recorded the highest ASRs in 2021. The male-to-female ratios for all ARSs increased globally from 1990 to 2021, with a significantly positive correlation between the gender ratios and SDI.
Conclusion: EC poses a growing challenge for elderly populations, with clear geographic and gender disparities. Targeted interventions are necessary to mitigate the increasing burden in older adults.
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http://dx.doi.org/10.1097/MCG.0000000000002241 | DOI Listing |
Turk J Pediatr
September 2025
Division of Developmental Pediatrics, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Türkiye.
Background: Autism spectrum disorder (ASD) is more frequently diagnosed in boys than in girls, possibly due to gender-based differences in symptom presentation or referral patterns. This study investigates gender-related variations in symptom severity and clinical presentation among preschool children referred for suspected ASD.
Methods: This study included 125 children (boys: n=103; girls: n=22) aged 2-5 years suspected of having ASD.
Turk J Pediatr
September 2025
Department of Pediatric Neurology, Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Türkiye.
Background: Children with cerebral palsy (CP) may experience epilepsy and challenges with movement, posture, cognition, and musculoskeletal development, which can impact their quality of life (QOL). In this study, we investigated the relationship between demographic and clinical variables as well as QOL in children with spastic CP.
Methods: Children aged 6 to 12 years with CP who were followed-up at our tertiary center were included in this cross-sectional study, regardless of the cause.
Turk J Pediatr
September 2025
Department of Public Health, Faculty of Medicine, Ankara Yıldırım Beyazıt University, Ankara, Türkiye.
Background: The ongoing conflict in Gaza continues to take an unbearable toll, with particularly severe impacts on children. Measuring the burden of conflict-related disease in Gaza in terms of disability-adjusted life years (DALYs) is important in terms of showing this effect. The aim of this study was to calculate the conflict-related DALY in Gaza among children aged 0-14 years, following the October 7 events and compare these values with global and expected values.
View Article and Find Full Text PDFTurk J Pediatr
September 2025
Division of Adolescent Health, Department of Pediatrics, University of Ottawa, Children's Hospital of Eastern Ontario (CHEO), Ottawa, Ontario, Canada.
Background: Food addiction has been increasingly recognized as a contributing factor to obesity and eating disorders. Compulsive eating, characterized by an uncontrollable urge to consume food despite adverse consequences, shares behavioral similarities with substance addiction. This study aims to adapt the Brief Measure of Eating Compulsivity (MEC) into Turkish and evaluate its validity and reliability in the adolescent population.
View Article and Find Full Text PDFJMIR Res Protoc
September 2025
University of Nevada, Las Vegas, Las Vegas, NV, United States.
Background: In-hospital cardiac arrest (IHCA) remains a public health conundrum with high morbidity and mortality rates. While early identification of high-risk patients could enable preventive interventions and improve survival, evidence on the effectiveness of current prediction methods remains inconclusive. Limited research exists on patients' prearrest pathophysiological status and predictive and prognostic factors of IHCA, highlighting the need for a comprehensive synthesis of predictive methodologies.
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