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Study DesignA cross-sectional retrospective study.ObjectivesThis study aims to analyze the correlation between cervical disc degeneration grade and cervical imaging parameters and improve grade assessment objectivity and accuracy under the Miyazaki disc degeneration grading system.MethodsCervical disc degeneration was graded using the Miyazaki disc degeneration grading system. Cervical imaging parameters included the disc height index (DHI) and segmental range of motion (sROM) in the lateral X-ray view. Correlation, subgroup analysis, and linear regression analysis were conducted to analyze the relationships between cervical disc degeneration grades, DHI, and sROM, respectively. The kappa value for the Miyazaki disc degeneration grading system was analyzed before and after considering imaging parameters.ResultsA total of 98 patients (47 males and 51 females, age from 29 to 85 years ) with 490 discs were included in the analysis. Correlation analysis revealed that cervical disc degeneration grade related to DHI (ρ = -0.543, < 0.001) and sROM (ρ = -0.309, < 0.001) across different cervical segments, age, sex, and body mass index groups (majority of < 0.05). Linear regression analysis illustrated a negative impact of the cervical disc degeneration grade on DHI (B = -0.058, < 0.001) and sROM (B = -0.903, < 0.001). Regarding the regression coefficients, the kappa value for the Miyazaki disc degeneration grading system increased from 0.626 to 0.812.ConclusionsCervical disc degeneration grade was associated with DHI and sROM in adult patients, and reference to cervical imaging parameters could improve the objectivity and accuracy of the Miyazaki disc degeneration grading system.
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http://dx.doi.org/10.1177/21925682251376337 | DOI Listing |
J Orthop Sci
September 2025
Department of Orthopedic Surgery, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Background: Cervical spine radiography is a common screening tool for cervical spondylosis with radiographic features, including osteophytes, disc height narrowing, vertebral sclerosis, and spondylolisthesis. The Kellgren-Lawrence classification is widely used for evaluating musculoskeletal radiographs, including spinal radiographs; however, evaluating the individual radiographic features of spondylosis is challenging with this classification. This study aimed to develop an elemental grading system for evaluating cervical spine radiographs and the extent of cervical spondylosis.
View Article and Find Full Text PDFGlobal Spine J
September 2025
Department of Orthopaedic Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Study DesignRetrospective cohort study.ObjectiveCondoliase is a chemonucleolysis for lumbar disc herniation (LDH) that enzymatically degrades herniated disc material with high specificity for chondroitin sulfate and hyaluronic acid. Few studies have compared condoliase treatment with surgical treatments.
View Article and Find Full Text PDFEur Spine J
September 2025
Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Purpose: To compare the long-term clinical outcomes and radiographic findings between hybrid surgery (HS) and anterior cervical discectomy and fusion (ACDF) for three-level cervical degenerative disc disease (CDDD). And the incidence, prognosis, and potential risk factors of heterotopic ossification (HO) more than 10 years after Bryan prosthesis replacement in HS has been explored.
Methods: From January 2007 to December 2014, a total of 46 patients who underwent either HS (n = 26) or ACDF (n = 20) for consecutive three-level CDDD were retrospectively analyzed.
Parasitol Int
September 2025
College of Life Science and Engineering, Foshan University, Foshan, Guangdong 528231, China. Electronic address:
Assemblage E of Giardia duodenalis, primarily infecting ruminants, has been relatively understudied both in vivo and in vitro. Due to unsuccessful attempts at in vitro cultivation, this study focused on establishing an economical, stable, and clinically relevant experimental animal model for Assemblage E infections. Cysts were purified from bovine feces via 33 % zinc sulfate flotation, with Assemblage E identity confirmed by gdh gene sequencing.
View Article and Find Full Text PDFJ Bone Joint Surg Am
September 2025
Department of Orthopedic Surgery, Columbia University and NewYork-Presbyterian Och Spine Hospital, New York, NY.
➢ For primarily scoliotic deformities, the principles of the modular Lenke classification for adult idiopathic scoliosis can be used to guide level selection.➢ For hyperkyphotic deformities, the upper end vertebra is a suitable upper instrumented vertebra. The sagittal stable vertebra or the first lordotic vertebra is appropriate for the lower instrumented vertebra when fusion to the sacrum is not required.
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