Publications by authors named "Masato Uematsu"
Study DesignRetrospective cohort study.ObjectiveCondoliase is a chemonucleolysis for lumbar disc herniation (LDH) that enzymatically degrades herniated disc material with high specificity for chondroitin sulfate and hyaluronic acid. Few studies have compared condoliase treatment with surgical treatments.
View Article and Find Full Text PDFPurpose: To identify risk factors for cement leakage (CL) in spinal fusion surgery using cement-augmented fenestrated pedicle screw (CAFPS). As a secondary objective, clinical outcomes were compared between CAFPS and conventional pedicle screw (CPS) in patients with osteoporosis.
Methods: We included 67 patients (272 screws) who underwent spinal fusion surgery with CAFPS and 104 patients with CPS.
Due to symptomatic gait imbalance and a high incidence of falls, patients with cervical disease-including degenerative cervical myelopathy-have a significantly increased risk of fragility fractures. To prevent such fractures in patients with cervical disease, treating osteoporosis is an important strategy. This study aimed to validate the diagnostic yield of a deep learning algorithm for detecting osteopenia/osteoporosis using cervical radiography and compare its diagnostic accuracy with that of spine surgeons.
View Article and Find Full Text PDFStudy Design: Multicenter retrospective cohort study.
Objective: To evaluate the efficacy and safety of using cement-augmented pedicle screw (CAPS) fixation only for the cephalad and caudal vertebral bodies.
Summary Of Background Data: Pedicle screw fixation is less effective in patients with low-quality bone.
Article Synopsis
- Orthotic treatment is commonly used for osteoporotic vertebral fractures (OVF), but there's limited evidence on its effectiveness, leading to this study investigating its clinical benefits.
- The research involved a retrospective cohort study of 160 patients with fresh OVF, comparing outcomes between those who wore braces and those who did not, measuring factors like pain levels and vertebral height over time.
- The results showed no significant improvement in pain or vertebral height between the brace and no-brace groups; however, the angular change in fractured vertebrae was notably less in patients using braces, particularly rigid braces, suggesting some benefits in fracture stability.
The Efficacy of Systemic Transdermal Diclofenac Patch for Postoperative Pain After Lumbar Spinal Surgery.
Spine (Phila Pa 1976)
February 2025
Article Synopsis
- The study was a single-center, prospective, comparative investigation designed to assess the effectiveness and safety of a transdermal diclofenac patch for pain relief after lumbar spinal surgery.
- It involved two groups: patients treated with the patch (DP [+]) and those who were not (DP [-]), with various pain measures and opioid use compared between them.
- Results showed that the DP (+) group used fewer rescue analgesics and reported lower pain scores shortly after surgery without significant renal complications, suggesting the patch may be a beneficial option for postoperative pain management.*
Neuroleptic malignant syndrome (NMS) with characteristic symptoms is a potentially lethal reaction to antipsychotic drugs. Atypical NMS usually lacks major symptoms and frequently occurs after treatment using atypical antipsychotics, such as aripiprazole. A 64-year-old man developed aripiprazole-induced NMS after surgery, and our early recognition of the NMS was based on high creatine kinase levels and low serum iron levels.
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