98%
921
2 minutes
20
Isolated bilateral temporalis muscle hypertrophy (IBTMH) is a rare clinical condition characterized by symmetrical enlargement of the temporalis muscles without masseter involvement. This case report presents a 47-year-old male with progressive bilateral temporal swelling and discomfort during mastication, significantly affecting his quality of life. Clinical examination and magnetic resonance imaging (MRI) confirmed homogenous enlargement of the temporalis muscles with no underlying pathology. The patient was treated with botulinum toxin type A (BTxA) injections in two sessions, following anatomical landmarks and established guidelines to ensure safety and efficacy. Post-treatment follow-ups revealed significant improvement in symptoms and normalization of temporal contours, with MRI confirming muscle volume reduction. This case contributes to the limited literature on IBTMH and supports BTxA as a safe, non-invasive, and effective treatment modality. It also underscores the need for standardized injection techniques to minimize complications in the anatomically complex temporal region. Further case reports and research are essential to improve clinical understanding and guide best practices for diagnosis and management of this rare entity.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405770 | PMC |
http://dx.doi.org/10.5125/jkaoms.2025.51.4.254 | DOI Listing |
Cureus
August 2025
Norton College of Medicine, SUNY Upstate Medical University, Syracuse, USA.
Hydralazine is an antihypertensive that can induce immune-related adverse effects, such as hydralazine-induced lupus and hydralazine-induced antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitis (AAV). AAV involves necrotizing inflammation of small blood vessels, manifesting as fever, malaise, arthralgia, and myalgia, potentially leading to organ failure. Diagnosis includes clinical evaluation, serological testing for ANCA, and histopathological examination, confirmed by necrotizing granulomatous inflammation in affected tissues.
View Article and Find Full Text PDFEnviron Microbiol Rep
October 2025
Reference Center for Lactobacilli (CERELA-CONICET), San Miguel de Tucumán, Argentina.
Limosilactobacillus fermentum CRL2085, isolated from feedlot cattle rations, displayed high efficiency as a probiotic when administered to animals. A comprehensive genomic analysis was performed to elucidate the genetic basis underlying its probiotic potential. Fifteen genomic islands and CRISPR-Cas elements were identified in its genome.
View Article and Find Full Text PDFEpilepsy Behav
September 2025
Department of Clinical and Experimental Epilepsy, University College London, London the United Kingdom of Great Britain and Northern Ireland; MRI Unit, Chalfont Centre for Epilepsy, Bucks, the United Kingdom of Great Britain and Northern Ireland. Electronic address:
Memory functional MRI (fMRI) has been used to explore cognitive processing in people with refractory temporal lobe epilepsy (TLE) to predict memory decline after anterior temporal lobe resection (ATLR). Traditional studies employed univariate analysis (UVA), focusing on isolated voxel activity in mesial temporal regions. By contrast, multivariate pattern analysis (MVPA), examines distributed activity patterns , offering deeper insight into neural networks supporting cognitive functions.
View Article and Find Full Text PDFHeart Rhythm
September 2025
Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China. Electronic address:
Background: The effectiveness of ethanol infusion of the vein of Marshall (EIVOM) for persistent atrial fibrillation (AF) in patients with mitral valve replacement (MVR) remains to be determined.
Objectives: This study investigated the effectiveness and safety of EIVOM in catheter ablation of persistent AF in patients with MVR.
Methods: This is a retrospective case-control study.
Front Oncol
August 2025
Unidad de Neurología y Neurocirugía, Hospital General de México, Mexico City, Mexico.
Vestibular Schwannomas are frequent tumors of the cerebellopontine angle, classically presenting with cochlear and facial nerve alteration. They tend to have histopathological and intratumoral degeneration seen on MRI, and can cause CSF obstruction with hydrocephalus with subsequent visual loss. We present a case of bilateral visual loss from papilledema, with no history of hydrocephalus or increased intracranial pressure.
View Article and Find Full Text PDF