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Objective: To design and fabricate a universal donor tooth model for autotransplantation and evaluate its clinical application efficacy.
Methods: CBCT data of 1003 third molars were collected as donor tooth data and classified after preprocessing. Multi-point cloud registration was performed for each classified dataset, and the registered point clouds were fused to obtain the distribution of point clouds under a unified reference. After filtering, a preliminary model was generated. The point cloud boundaries of the preliminary model were extracted, and statistical calculations identified 12 model variants based on maxillary/mandibular position, single-root/multi-root anatomy, and dimensional variations. A total of 117 patients who received single-tooth autotransplantation were randomly divided into a universal model group and a customized model group. The two groups used the universal model and a customized 3D model printed preoperatively based on donor tooth CT data, respectively, to assist in preparing the alveolar socket of the recipient site. Statistical analysis was made on the observation indexes between the two groups.
Results: The number of times the alveolar socket of the recipient site was prepared with a donor tooth after preparation using universal model was significantly larger in the universal model group than that in the customized model group (P = 0.047), there were no statistically significant differences in initial postoperative stability (P = 0.069) or healing outcomes at 6 months postoperatively (P = 0.747).
Conclusion: The universal model for autotransplantation can simplify preoperative preparation, shorten the operation period, reduce surgical trauma and time costs. There is no significant difference in short-term healing outcomes between patients using the universal model and those using customized model, which is worthy of popularizing.
Clinical Significance Statement: The 3D printing technology has been widely used in the autotransplantation. However, obtaining the donor tooth model before operation requires preparation of technology, time and cost. The universal model of donor tooth based on clinical big data design can simplify preoperative preparation, reduce surgical trauma and time costs, and result a good short-term healing outcomes.
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http://dx.doi.org/10.1016/j.jdent.2025.106059 | DOI Listing |
Immun Inflamm Dis
September 2025
Department of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
Objectives: The current systematic review and meta-analysis aims to assess the safety and immunogenicity of the anticaries vaccines currently available.
Materials And Methods: Electronic searches of PubMed, Scopus, Web of Science and Science Direct were performed. Studies assessing the safety and effectiveness of the anticaries vaccination, including the dose, plasmids, serum IgG and IgA levels after immunization, were included.
Int Dent J
September 2025
Department of Periodontology, Peking University School and Hospital of Stomatology, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatolog
Introduction And Aims: Free gingival grafting (FGG) is a common procedure in periodontal and implant therapy to augment keratinized tissue and improve esthetic outcomes. However, the effects of graft dimensions and residual tissue thickness (RTT) on palatal donor site healing remain poorly characterized, lacking standardized 3-dimensional analysis. This study aimed to quantify how these factors influence 3-dimensional tissue recovery over 6 months, with thickness recovery rate as the primary outcome.
View Article and Find Full Text PDFWorld J Urol
September 2025
Department of Urology, Antwerp University Hospital, Antwerp, Belgium.
Purpose: To evaluate patient-reported oral health and pain and buccal donor site complications in adults who underwent BMG harvesting utilizing two validated questionnaires.
Materials And Methods: An ethics-approved prospective observational study was conducted among a cohort of 40 adults who had a BMG urethroplasty between June 2020 and October 2021. All cases were performed by one fellowship-trained genitourinary reconstructive surgeon.
Microorganisms
August 2025
Department of Oral Medicine and Diagnostics, College of Dentistry, University of Illinois Chicago, Chicago, IL 60607, USA.
Changes in health, lifestyle, and medication usage significantly impact overall well-being. Aging is associated with an increased need for multiple medications, or polypharmacy. Despite extensive research on how aging and polypharmacy affect the gut microbiome, relatively little is known about their impact on the oral microbiome and how shifts there can contribute to oral and systemic disease.
View Article and Find Full Text PDFJ Korean Assoc Oral Maxillofac Surg
August 2025
Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Korea.
Objectives: : Autotransplantation of third molars with complete root formation is a well-established surgical approach for replacing missing teeth, offering biological advantages over conventional prosthetic or implant therapies. The severity of third molar impaction may significantly influence autotransplantation prognosis, yet its clinical significance has not been thoroughly investigated.
Materials And Methods: : This retrospective cohort analysis assessed for autotransplantation of the third molar.