Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Hemorrhage, or severe blood loss due to injury, is a leading cause of preventable deaths after injury. This study uses and extends activity theory to understand the dynamics of team-based hemorrhage control during trauma resuscitation and to explore potential computerized mechanisms to support this time- and safety-critical process. We reviewed videos of 25 resuscitation cases and analyzed hemorrhage control activities using nine activity theory prompts, including a new prompt-speech intention-a critical but underexplored dimension of teamwork in prior activity theory analyses. Through this process, we identified the most common delay-causing activities and developed routine and non-routine activity models for each. A comparison of these models showed that variations from the routine models emerged due to changes in the division of labor, instruments, community, and speech intentions. We contribute to research on designing socio-technical systems by (1) identifying needs and opportunities for computerized support that address delays in complex medical teamwork and (2) examining how an intervention changes an activity model. We also show how adding detailed speech data aids in identifying contradictions between elements in an activity model.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12380369PMC
http://dx.doi.org/10.1145/3701195DOI Listing

Publication Analysis

Top Keywords

activity theory
12
hemorrhage control
8
activity model
8
activity
7
addressing teamwork
4
teamwork delays
4
delays life-saving
4
life-saving interventions
4
interventions activity
4
activity theory-informed
4

Similar Publications

Cyclin-dependent kinase 20 (CDK20), also known as cell cycle-related kinase (CCRK), plays a pivotal role in hepatocellular carcinoma (HCC) progression by regulating β-catenin signaling and promoting uncontrolled proliferation. Despite its emerging significance, selective small-molecule inhibitors of CDK20 remain unexplored. In this study, a known CDK20 inhibitor, ISM042-2-048, was employed as a reference to retrieve structurally similar compounds from the PubChem database using an 85% similarity threshold.

View Article and Find Full Text PDF

Emotional contagion is an important aspect of social interaction. Traditional theories suggest that it relies on mimicry of facial or emotional movements. To address the question of whether there is a distinction between emotional contagion and emotional mimicry, we conducted a meta-analysis using the ALE algorithm to identify brain regions activated by the two tasks.

View Article and Find Full Text PDF

A theoretical study on doping Pd-like superatoms into defective graphene quantum dots: an efficient strategy to design single superatom catalysts for the Suzuki reaction.

Nanoscale

September 2025

Fujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, The School of Pharmacy, Fujian Medical University, Fuzhou, Fujian 350122, People's Republic of China.

The rational design of non-precious metal catalysts as a replacement for Pd is of great importance for catalyzing various important chemical reactions. To realize this purpose, the palladium-like superatom NbN was doped into a defective graphene quantum dot (GQD) model with a double-vacancy site to design a novel single superatom catalyst, namely, NbN@GQD, based on density functional theory (DFT), and its catalytic activity for the Suzuki reaction was theoretically investigated. Our results reveal that this designed catalyst exhibits satisfactory activity with a small rate-limiting energy barrier of 25.

View Article and Find Full Text PDF

Accelerating Transition State Search and Ligand Screening for Organometallic Catalysis with Reactive Machine Learning Potential.

J Chem Theory Comput

September 2025

State Key Laboratory of Fine Chemicals, Frontiers Science Center for Smart Materials Oriented Chemical Engineering, Department of Pharmaceutical Sciences, Institute of Chemical Process Systems Engineering, School of Chemical Engineering, Dalian University of Technology, Dalian 116024, China.

Organometallic catalysis lies at the heart of numerous industrial processes that produce bulk and fine chemicals. The search for transition states and screening for organic ligands are vital in designing highly active organometallic catalysts with efficient reaction kinetics. However, identifying accurate transition states necessitates computationally intensive quantum chemistry calculations.

View Article and Find Full Text PDF

Ultrastable Copper Cluster Enables Highly Site-Selective and Chemoselective Carbocation C(sp)-H and C(sp)-H Bonds Functionalization.

J Am Chem Soc

September 2025

State Key Laboratory of Antiviral Drugs, Tianjian Laboratory of Advanced Biomedical Sciences, Pingyuan Laboratory, and College of Chemistry, Zhengzhou University, Zhengzhou 450001, China.

The C-H functionalization represents a universal and important method for constructing new C-C bonds by carrying out reactions directly on inert C-H bonds. The major challenges are to control the site-selectivity and chemoselectivity because most complex organic compounds have many similar C-H bonds or different functional groups, such as a C═C bond or O-H bond. Here, we develop a versatile copper cluster (CuNC) with high stability and dynamic catalytic sites.

View Article and Find Full Text PDF