Affective-cognitive circuits in postoperative appetite reduction: an adaptive neuroimmune response to surgical stress.

Front Neurosci

Center for Life Sciences, Yunnan Key Laboratory of Cell Metabolism and Diseases, School of Life Sciences, Yunnan University, Kunming, China.

Published: August 2025


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Postoperative reduction in appetite perception, conceptualized as an interplay between emotion, perception, and cognition, may lead to adverse nutritional outcomes. However, an increasing body of research suggests that it may serve as an adaptive mechanism to inhibit inflammatory responses and regulate metabolic burden. This review comprehensively summarizes the multifaceted mechanisms underlying postoperative changes in appetite perception, particularly from the perspectives of immune regulation, inflammatory suppression, and metabolic reprogramming. Special attention is paid to the affective and cognitive dimensions of appetite perception, exploring how emotion-related processing and neurocognitive feedback contribute to appetite perception suppression during recovery. Moreover, this review highlights the clinical significance of these affective-perceptual changes in postoperative nutritional management, emphasizing the need to integrate psychological, perceptual, and neuroimmune factors into patient care strategies. Ultimately, the article explores the potential role of postoperative appetite perception reduction in modulating insulin sensitivity and improving systemic metabolic health. Based on current literature, we advocate for reevaluating appetite perception dynamics during recovery to provide novel theoretical foundations and practical directions for targeted postoperative nutritional interventions.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12378390PMC
http://dx.doi.org/10.3389/fnins.2025.1654559DOI Listing

Publication Analysis

Top Keywords

appetite perception
24
postoperative appetite
8
postoperative nutritional
8
appetite
7
perception
7
postoperative
6
affective-cognitive circuits
4
circuits postoperative
4
appetite reduction
4
reduction adaptive
4

Similar Publications

The arginine-phenylalanine-amide neuropeptide receptor family: Physiological effects, drug development, and structural insights.

Neural Regen Res

September 2025

Kobilka Institute of Innovative Drug Discovery, Shenzhen Key Laboratory of Steroid Drug Discovery and Development, School of Medicine, The Chinese University of Hong Kong, Shenzhen, Guangdong Province, China.

The arginine-phenylalanine-amide neuropeptide receptor family comprises a subclass within the G protein-coupled receptor superfamily with crucial roles in physiological regulation. These receptors recognize and bind neuropeptides with an arginine-phenylalanine-amide motif, thereby participating in a variety of biological processes such as energy metabolism, pain perception, and reproductive functions. In this review, we explore the physiological and pathological processes involving these receptors and delve into the structure-activity relationships of their ligand peptides, clarifying the key structural motifs within these neuropeptides that determine their biological activity, pharmacological potency, and receptor selectivity.

View Article and Find Full Text PDF

Parent reports of eating behaviour and feeding practices: effects of parent and child sex.

Appetite

September 2025

School of Psychology and Institute of Health and Neurodevelopment, Aston University, Birmingham, UK. Electronic address:

Research on parental feeding practices has focused on mothers, often overlooking fathers' perspectives and the influence of child sex. This study examined (1) differences between fathers' and mothers' own eating behaviours, their use of feeding practices, and perceptions of their children's eating behaviours, and (2) the role of child sex in these perceptions and practices. Parents (N = 784; 145 fathers and 639 mothers) of preschoolers (3-5 years, 51.

View Article and Find Full Text PDF

The marketing and commercialization of infant formula have been identified as major barriers to breastfeeding, influencing parental feeding choices through a wide range of strategies that include persuasive packaging elements. This work explores how mothers in Uruguay perceive infant formula packaging and examines the influence of marketing elements on their perceptions and behavioral intentions. An exploratory sequential mixed-methods design was employed, combining semi-structured interviews with a randomized controlled trial.

View Article and Find Full Text PDF

Veterinarians' perceptions on African swine fever and the control measures in Estonia.

Acta Vet Scand

August 2025

Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, F.R.Kreutzwaldi, 51014, Tartu, Estonia.

Background: Veterinarians are key stakeholders in fighting African Swine Fever (ASF), yet their awareness, perceptions and attitudes of ASF are often unknown. This is crucial, especially in Estonia where ASF has persisted for almost 10 years. We conducted five focus groups involving 11 farm veterinarians and 4 assistants working on Estonian commercial pig farms.

View Article and Find Full Text PDF

Affective-cognitive circuits in postoperative appetite reduction: an adaptive neuroimmune response to surgical stress.

Front Neurosci

August 2025

Center for Life Sciences, Yunnan Key Laboratory of Cell Metabolism and Diseases, School of Life Sciences, Yunnan University, Kunming, China.

Postoperative reduction in appetite perception, conceptualized as an interplay between emotion, perception, and cognition, may lead to adverse nutritional outcomes. However, an increasing body of research suggests that it may serve as an adaptive mechanism to inhibit inflammatory responses and regulate metabolic burden. This review comprehensively summarizes the multifaceted mechanisms underlying postoperative changes in appetite perception, particularly from the perspectives of immune regulation, inflammatory suppression, and metabolic reprogramming.

View Article and Find Full Text PDF