Mothers' perceptions of marketing elements on infant formula packages: A mixed-methods exploration in Uruguay.

The marketing and commercialization of infant formula have been identified as major barriers to breastfeeding, influencing parental feeding choices through a wide range of strategies that include persuasive packaging elements. This work explores how mothers in Uruguay perceive infant formula packaging and examines the influence of marketing elements on their perceptions and behavioral intentions. An exploratory sequential mixed-methods design was employed, combining semi-structured interviews with a randomized controlled trial.

Application of Microwaves to Reduce Checking in Low-Fat Biscuits: Impact on Sensory Characteristics and Energy Consumption.

The use of microwaves (MWs) has been proposed as an energy-efficient method for reducing checking. Along with understanding moisture distribution, it is essential to consider structural characteristics to explain how MWs reduce checking. The influence of MWs on these characteristics depends on the food matrix's dielectric and viscoelastic properties, which vary significantly between fresh and pre-baked dough.

Fetal renal ultrasonography in canine pregnancy: relationship with maternal and fetal metrics for assessing fetal maturity.

Accurate estimation of gestational age is essential in canine obstetrics to optimize the timing of parturition and reduce neonatal risk. This study investigated the correlation between fetal kidney biometry and established gestational indicators in pregnant bitches. Fifty clinically healthy bitches underwent serial ultrasonographic evaluations between Days 40 and 63 of gestation.

EMT and cancer stem cells: Drivers of therapy resistance and promising therapeutic targets.

Cancer continues to be a primary cause of death, resulting in substantial mortality and illness globally. It remains a significant global health issue, greatly affecting morbidity and mortality across the world. Therapeutic resistance poses a major challenge to cancer treatments, acting as a significant barrier to the effectiveness of both standard and targeted therapies.

Efficacy of decellularized extracellular matrix (dECM) for articular cartilage repair in osteoarthritis (OA): a systematic review and meta-analysis.

Background: Osteoarthritis (OA) is a common degenerative joint disease causing chronic pain, disability, and mobility limitations, severely affecting quality of life. Traditional treatments like physical therapy and surgery often have limited efficacy due to side effects, incomplete recovery, and disease progression, highlighting the need for innovative therapies.

Methods: We searched PubMed and Embase from January 1, 2010 to November 1, 2024, preliminary included studies involving animal experiments on the therapeutic effects of decellularized extracellular matrix (dECM) and its derived materials on cartilage defect.

Treating diabetic foot ulcers with antimicrobial wound dressing impregnated with dialkylcarbamoyl chloride.

Objective: Diabetic foot ulcers (DFUs) are at significant risk of becoming infected, with an associated elevated risk of amputation. Choosing an appropriate treatment would help prevent infection, improve healing and patients' quality of life, as well as reduce healthcare costs. The aim of this study was to assess the efficacy of a dialkylcarbamoyl chloride (DACC)-coated wound dressing to reduce bacterial load in the treatment of infected diabetic foot ulcers with signs of biofilm.

Factors influencing parental decisions on food choices during complementary feeding: a qualitative study in Uruguay.

Understanding parental decision-making during complementary feeding is essential for designing effective interventions that address deviations from nutritional recommendations and support optimal growth and development. However, there is no consensus on the key factors shaping the characteristics of complementary feeding, particularly in Africa, Asia, and Latin America. In this context, the present work aimed to identify factors influencing parental decision-making on what foods to offer their child during complementary feeding in Uruguay, a Latin American country.

Neonatal blood lactate as a predictor of early survival in puppies delivered by emergency cesarean section.

This study evaluated blood lactate as a biomarker of neonatal viability in puppies delivered by emergency cesarean section. A total of 28 bitches and 118 neonates were assessed for weight, temperature, plasma lactate and glucose levels, and Apgar scores immediately after birth. Eighteen neonates (15.

Automated high-throughput RP-HPLC-MS and SFC-MS analytical and purification platforms to support drug discovery.

In recent years, the need to accelerate drug discovery processes in the pharmaceutical industry has revived the interest of implementing automated workflows, allowing the simultaneous processing of multiple samples on global processes that are referred as High-Throughput Purification (HTP). In this work, SAPIO Laboratory Information Management System (SAPIO LIMS) has been customized at the HTP laboratories of Janssen R&D to accommodate the needs of global purification groups on several automated HTP workflows, integrating Analytical Studio™ data processing tool on multiple steps. Herein we describe the workflow details from crude analysis via RP-LC-MS or SFC-MS systems to sample redissolution and delivery to Compound Logistics (CL) in tubes ready for assay plate preparation.

High-fidelity color characterization in virtual reality across head mounted displays, game engines, and materials.

We present a comprehensive colorimetric analysis of three head mounted displays (HMDs) - HTC Vive Pro Eye, Pimax 8K X DMAS, and Varjo Aero - focusing on their color calibration and uniformity across different game engines (Unity and Unreal) and for different materials/shaders. We developed a robust methodology combining hardware and software tools, including spectroradiometry and imaging colorimetry, to characterize and calibrate these HMDs for accurate color reproduction. The study showcases substantial advancements in colorimetric accuracy, with a reduction in the average deltaE00 of 90 or more across all tested HMDs and conditions.

A qualitative exploration of mothers' perspectives on infant formula use in Uruguay.

The transformation of the first-food systems and the widespread availability and marketing of breastmilk substitutes undermine efforts to promote adequate breastfeeding practices. The objective of the present research was to explore mothers' perspectives on infant formula use in Montevideo, the capital of Uruguay. A generic qualitative design was used to explore mothers' perspectives on the factors that act as enablers or barriers for infant formula use.

Novel Determination of Functional Groups in Partially Acrylated Epoxidized Soybean Oil.

The acrylation degree of vegetable oils plays a relevant role in determining the mechanical properties of the resulting polymers. Both epoxide and acrylate functionalities participate in polymerization reactions, producing various types of chemical bonds in the polymer network, which contribute to specific properties such as molecular size distribution, crosslinking degree, and glass transition temperature (Tg). The accurate identification of epoxide and acrylated groups in triglyceride molecules helps to predict their behavior during the polymerization process.

Factors Influencing Health Professionals' Decisions Regarding the Indication of Infant Formula: A Qualitative Exploration in Uruguay.

Background: Health systems are fundamental to the promotion and protection of breastfeeding. Health professionals have a pivotal influence on families' infant feeding decisions and may act as facilitators or barriers to adequate breastfeeding practices.

Research Aim: To explore factors influencing health professionals' decisions regarding the indication of infant formula in Montevideo, the capital of Uruguay, an emerging Latin American country.

Direct Acrylation of Soybean Oil and the Influence of the Acrylation Degree on Waterborne Acrylic Systems.

The direct acrylation of soybean oil was investigated by the activation of soybean oil's (SO's) internal fatty unsaturation with acidic catalysts. The effect of the catalyst and the reactant ratio with respect to the unsaturation and reaction time on the direct acrylation process were explored. ASO (acrylated soybean oil) with acrylation degrees (the number of acrylate molecules introduced in a triglyceride molecule) between 1.

Maternal and fetal factors for determining the cesarean section type (scheduled/emergency) in bitches.

One hundred and forty bitches and their offspring (689 puppies) were involved in this study. The influence of different maternal features such as age, breed (brachycephalic/non-brachycephalic), previous births (primiparous/multiparous), health status (complete/incomplete) and litter size over the type of cesarean sections (scheduled/emergency), the neonatal survival, and the incidence of congenital malformations were also examined. Scheduled cesareans were predominant (104/140), of which 90 % were brachycephalic breeds and females were mostly between 2 and 4 years old (54.

Pan-cancer analysis of T-cell proliferation regulatory genes as potential immunotherapeutic targets.

T cells are the key to killing tumor cells. However, the exact mechanism of their role in cancer is not fully understood. Therefore, a comprehensive understanding of the role of T-cell proliferation regulatory genes in tumors is needed.

Effect of lung volume preservation during spontaneous breathing trial on successful extubation in patients receiving mechanical ventilation: protocol for a multicenter clinical trial.

Background: In standard weaning from mechanical ventilation, a successful spontaneous breathing test (SBT) consisting of 30 min 8 cmHO pressure-support ventilation (PSV8) without positive end-expiratory pressure (PEEP) is followed by extubation with continuous suctioning; however, these practices might promote derecruitment. Evidence supports the feasibility and safety of extubation without suctioning. Ultrasound can assess lung aeration and respiratory muscles.

Beyond Needles: Pioneering Pediatric Care with Virtual Reality (VR) for TIVAD Access in Oncology.

Introduction: Pediatric oncology patients use totally implantable venous access devices (TIVADs) to enable central venous access. Anxiety, pain and/or discomfort are common despite anesthesia. Virtual reality (VR) is a non-pharmacological approach that may reduce pain and anxiety in these patients.

The effect of thermostable and enteric-coated multi-protease on the performance and digestibility of laying hen fed low-protein diets.

This study evaluated the efficacy of a multi-protease on the performance, egg quality and digestibility of laying hen. The study had four treatments: Control (without multi-protease, CON), Pro 1.2 (CON + 0.

The comprehensive landscape of prognosis, immunity, and function of the GLI family by pan-cancer and single-cell analysis.

The Hedgehog (Hh) signaling pathway has been implicated in the pathogenesis of various cancers. However, the roles of the downstream GLI family (GLI1, GLI2, and GLI3) in tumorigenesis remain elusive. This study aimed to unravel the genetic alterations of GLI1/2/3 in cancer and their association with the immune microenvironment and related signaling pathways.

Effect of dietary inclusion of Bacillus-based probiotics on performance, egg quality, and the faecal microbiota of laying hen.

Objective: Our study examined the impact of propriety blends of Bacillus strain probiotics on the performance, egg quality, and faecal microflora of laying hens.

Methods: A total of 183 Institut de selection Animale (ISA) brown laying hens aged 23 weeks with an average body weight of 1,894±72 g were randomly allocated into 3 groups as control (corn-soybean meal based diet, CON), 0.5 g/kg Enterosure probiotics (ET1, 3×108 colony-forming unit [CFU]/kg feed), and 5 g/kg Enterosure probiotics (ET2, 3×109 CFU/kg feed) administered in mashed form.

Systematic analysis of the prognostic value and immunological function of LTBR in human cancer.

Lymphotoxin beta receptor (LTBR) is a positive T cell proliferation regulator gene. It is closely associated with the tumor immune microenvironment. However, its role in cancer and immunotherapy is unclear.

Crystal Structure and Enzymology of Inositol Tris/Tetrakisphosphate Kinase 1 (ITPK1).

Inositol phosphates and their pyrophosphorylated derivatives are responsive to the phosphate supply and are agents of phosphate homeostasis and other aspects of physiology. It seems likely that the enzymes that interconvert these signals work against the prevailing milieu of mixed populations of competing substrates and products. The synthesis of inositol pyrophosphates is mediated in plants by two classes of ATP-grasp fold kinase: PPIP5 kinases, known as VIH, and members of the inositol tris/tetrakisphosphate kinase (ITPK) family, specifically ITPK1/2.