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The latent class model has been proposed as a powerful tool in understanding human behavior for various fields such as social, psychological, behavioral, and biological sciences. However, one important limitation of the latent class model is that it is primarily applied to data with binary responses or categorical responses, making it fail to model real-world data with continuous or negative responses. In many applications, ignoring the weights throws out a lot of potentially valuable information contained in the weights. To address this limitation, we propose a novel generative model, the arbitrary-distribution latent class model (adLCM). Our model enables the generation of data's response matrix from an arbitrary distribution with a latent class structure. When compared to the latent class model, our adLCM is both more realistic and general. To our knowledge, our adLCM is the first model for latent class analysis with any real-valued responses, including continuous, negative, and signed values, thereby extending the classical latent class model beyond its traditional limitation to binary or categorical outcomes. We investigate the identifiability of the model and propose an efficient algorithm for estimating the latent classes and other model parameters. We show that the proposed algorithm enjoys consistent estimation. The performance of our algorithm is evaluated using both computer-generated data and real-world personality test data.
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http://dx.doi.org/10.3390/e27080866 | DOI Listing |
J Pers
September 2025
Department of Developmental Psychology, Tilburg University, Tilburg, the Netherlands.
Objective: In recent decades, increased freedom of choice and advancements in fertility regulation have allowed individuals to follow different fertility paths. This greater autonomy provides room for personality traits to shape long-term fertility expectations, which in turn can be predictive of fertility outcomes. The present study investigates how Big Five personality traits are related to fertility expectations trajectories and outcomes.
View Article and Find Full Text PDFFront Psychiatry
August 2025
Department of Neurosurgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Introduction: Anxiety, depression, and insomnia are common among older patients with tuberculosis (TB), yet their associations with inflammatory responses and drug-induced liver injury (DILI) remain insufficiently explored. This study aimed to identify distinct inflammation-DILI phenotypes in older TB patients and examine differences in anxiety, depression, and insomnia across subgroups.
Methods: In this cross-sectional study, 251 older TB patients were evaluated.
Ren Fail
December 2025
Department of Rehabilitation Medicine, Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Background: Depression is a common mental disorder in hemodialysis patients. The present study aimed to identify subgroups of patients receiving hemodialysis based on depression and explore the influencing factors in a multicenter hemodialysis population in China.
Methods: A total of 1,090 hemodialysis patients (682 men, mean aged 61.
J Public Health Policy
September 2025
Carrera de Medicina, Universidad Nacional de Loja, Av. Pio Jaramillo Alvarado, 110150, Loja, Ecuador.
Poor quality obstetric care can harm women's mental health, especially after childbirth. This study examines how the perceived quality of health services during childbirth is related to postpartum depression in Ecuador. Using data from 16,451 women in the 2018 National Health and Nutrition Survey, we applied probit and latent class probit models.
View Article and Find Full Text PDFPediatr Res
September 2025
Division of Developmental and Behavioral Pediatrics, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
Background: Children with congenital cytomegalovirus (cCMV) have a wide spectrum of possible neurodevelopmental outcomes.
Objectives: To describe neurodevelopmental (ND) Phenotypes of children with cCMV based on medical, developmental, and behavioral outcomes in childhood, and examine whether birth characteristics were associated with ND Phenotype.
Methods: Caregivers of children with cCMV (N = 242, child aged 12 months to <11 years) completed survey instruments reporting on the child's birth characteristics, reasons for cCMV testing, and present medical, developmental, and behavioral status.