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To address the issues of poor thermal stability, inadequate salt tolerance, and environmental risks in conventional gel systems for the development of high-temperature, high-salinity heterogeneous reservoirs, a triple-synergy gel system comprising anionic polyacrylamide (APAM), polyethyleneimine (PEI), and phenolic resin (SMP) was developed in this study. The optimal synthesis parameters-APAM of 180 mg/L, PEI:SMP = 3:1, salinity of 150,000 ppm, and temperature of 110 °C-were determined via response surface methodology, and a time-viscosity model was established. Compared with existing binary systems, the proposed gel exhibited a mass retention rate of 93.48% at 110 °C, a uniform porous structure (pore size of 2-8 μm), and structural stability under high salinity (150,000 ppm). Nuclear magnetic resonance displacement tests showed that the utilization efficiency of crude oil in 0.1-1 μm micropores increased to 21.32%. Parallel dual-core flooding experiments further confirmed the selective plugging capability in heterogeneous systems with a permeability contrast of 10:1: The high-permeability layer (500 mD) achieved a plugging rate of 98.7%, while the recovery factor of the low-permeability layer increased by 13.6%. This gel system provides a green and efficient profile control solution for deep, high-temperature, high-salinity reservoirs.
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http://dx.doi.org/10.3390/gels11080669 | DOI Listing |
J Drug Target
September 2025
Department of Pharmacology, Rajarshi Shahu College of Pharmacy, Buldana, Maharashtra, INDIA.
Natural phytoconstituents such as betanin and curcumin have attracted interest for their significant antioxidant and anti-inflammatory properties. Their therapeutic efficacy is notably constrained by inadequate bioavailability and reduced skin permeability. The current study developed an ethosome-based gel system for the delivery of betanin and curcumin, with the objective of improving transdermal penetration and providing sustained anti-inflammatory effects.
View Article and Find Full Text PDFJ Mater Chem B
September 2025
Department of Chemistry, Indian Institute of Technology Ropar, Rupnagar, Punjab 140001, India.
The unregulated use and improper disposal of active pharmaceutical ingredients (APIs), particularly phenylbutazone (PBZ), are contaminating water resources and posing serious risks to the food chain. PBZ is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for treating pain and fever in animals, and its persistence in the environment due to inadequate waste management has become a cause of concern. To address this, we report the fabrication of benzimidazole-based self-assembled nanomicelles (R2 NMs) for selective detection and removal of PBZ.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
College of Materials Science and Engineering, Hunan University, Changsha 410082, China.
Modern electronic systems are evolving toward miniaturized designs, flexible architectures, and high-power-density requirements. However, progress in developing electrical insulation materials that integrate mechanical robustness, flexibility, and thermal stability remains a critical challenge. This study introduces a novel nacre-inspired aramid-vermiculite nanopaper featuring a 3D interconnected layered network, designed for use in flexible electrical insulating applications.
View Article and Find Full Text PDFInt J Food Microbiol
September 2025
Department of Food Science and Nutrition, Faculty of Food Engineering, University of Campinas, Campinas, SP, Brazil. Electronic address:
This study investigated the presence of Pseudomonas aeruginosa and heterotrophic bacteria in 1150 samples of bottled mineral water. P. aeruginosa was initially isolated using membrane filtration on selective agar and subsequently confirmed by PCR.
View Article and Find Full Text PDFSmall
September 2025
Department of Materials Science and Engineering, Ludong University, Yantai, 264025, China.
With the continuous development of flexible sensors and flexible energy storage devices, gel materials with good flexibility, toughness, and tunable properties have attracted wide attention. Deep eutectic solvents (DES) have an obvious advantage of thermal and chemical stability over water. Therefore, eutectogels can effectively solve the problem of insufficient stability of traditional hydrogels.
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