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Continuous monitoring of respiratory patterns is essential for disease diagnosis and daily health care. Contact medical devices enable reliable respiratory monitoring, but can cause discomfort and are limited in some settings. Radar offers a noncontact respiration measurement method for continuous, real-time, high-precision monitoring. However, it is difficult for a single radar to characterize the coordination of chest and abdominal movements during measured breathing. Moreover, motion interference during prolonged measurements can seriously affect accuracy. This study proposes a dual radar system with customized narrow-beam antennas and signals to measure the chest and abdomen separately, and an adaptive dynamic time warping (DTW) algorithm is used to effectively suppress motion interference. The system is capable of reconstructing respiratory waveforms of the chest and abdomen, and robustly extracting various respiratory parameters via motion interference. Experiments on 35 healthy subjects, 2 patients with chronic obstructive pulmonary disease (COPD), and 1 patient with heart failure showed a high correlation between radar and respiratory belt signals, with correlation coefficients of 0.92 for both the chest and abdomen, a root mean square error of 0.80 bpm for the respiratory rate, and a mean absolute error of 3.4° for the thoracoabdominal phase angle. This system provides a noncontact method for prolonged respiratory monitoring, measurement of chest and abdominal asynchrony and apnea detection, showing promise for applications in respiratory disorder detection and home monitoring.
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http://dx.doi.org/10.3390/bios15080486 | DOI Listing |
Adv Sci (Weinh)
September 2025
Key Laboratory of Emergency and Trauma of Ministry of Education, The First Affiliated Hospital, NHC Key Laboratory of Tropical Disease Control, School of Tropical Medicine & The Second Affiliated Hospital, Hainan Medical University, Haikou, 571199, China.
Circulating tumor cells (CTCs) carry intact tumor molecular information, making them invaluable for personalized cancer monitoring. However, conventional capture methods, relying on passive diffusion, suffer from low efficiency due to insufficient collision frequency, severely limiting clinical utility. Herein, a magnetic micromotor-functionalized DNA-array hunter (MMDA hunter) is developed by integrating enzyme-propelled micromotors, magnetic nanoparticles, and nucleic acid aptamers into distinct functional partitions of a DNA tile self-assembly structure.
View Article and Find Full Text PDFCurr Biol
August 2025
Department of Cognitive, Linguistic, and Psychological Sciences, Brown University, 190 Thayer Street, Providence, RI 02912, USA.
Across various types of learning and memory, when a new training session follows a previous one after a certain temporal interval, the previously acquired learning can be disrupted-an effect known as retrograde interference (RI) or catastrophic forgetting. This disruption is thought to result from disrupting interactions between the learning of the first-trained task and the learning of the second-trained task while the former has not yet stabilized. Such destructive interactions have been considered characteristic not only of RI but also of related phenomena.
View Article and Find Full Text PDFMagn Reson Med
September 2025
A.I. Virtanen Institute, University of Eastern Finland, Kuopio, Finland.
Since its introduction more than 30 years ago, the blood oxygenation level-dependent (BOLD) contrast remains the most widely used method for functional MRI (fMRI) in humans and animal models. The BOLD contrast is typically acquired with echo planar imaging (EPI) to obtain sensitization of the signal during the echo time (TE) to dynamic changes in deoxyhemoglobin content, while achieving high spatiotemporal resolution and full brain coverage. However, EPI-based fMRI also faces multiple shortcomings, including sensitivity to body motion, susceptibility-related signal dropouts, interference with multimodal sensors, and loud acoustic noise.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
The Institute of Precision Machinery and Smart Structure, College of Engineering, Zhejiang Normal University, Jinhua, Zhejiang 321004, China.
Flexible sensors integrating motion detection and tactile perception capabilities demonstrate significant potential in aerospace biomechanics and medical rehabilitation. Here, we report a biomimetic inflatable chamber sensor that synergistically integrates pneumatic-auxiliary and electronic sensing for elbow joint health monitoring. The device architecture combines multiwalled carbon nanotube-reinforced silicone composites with embedded electrode arrays integrated within the inner lining of inflatable chambers, achieving high sensitivity while maintaining signal stability under electromagnetic interference.
View Article and Find Full Text PDFMed Sci Monit
September 2025
Department of Psychiatry, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.
This review comprehensively examines the application and progress of functional near-infrared spectroscopy (fNIRS) in schizophrenia research. Schizophrenia is a complex neuropsychiatric disorder characterized by extensive dysfunction in the prefrontal-limbic system and dysregulation of brain network connectivity. fNIRS, with its advantages of high portability, resistance to motion interference, and non-invasive real-time monitoring of cerebral hemodynamic responses, has emerged as a valuable tool in exploring the neural mechanisms of schizophrenia.
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