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http://dx.doi.org/10.1002/jha2.70106 | DOI Listing |
Leuk Res Rep
August 2025
Division of Hematology/Oncology, Department of Medicine, UMass Chan Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.
Myeloid sarcomas (MS) are rare extramedullary manifestations of myeloid progenitor cells occurring with or without acute myeloid leukemia. Peritoneal MS is exceptionally uncommon, with no established treatment guidelines, but treatment has historically consisted of cytotoxic chemotherapy. We present the case of a 78-year-old female with 60% CD34+, HLA-DR+, and CD33+ myeloblasts in ascitic fluid, while bone marrow biopsy demonstrated only molecular evidence of the leukemic clone with , and mutations.
View Article and Find Full Text PDFIndian Pediatr
July 2025
Department of Medical Oncology, Dr. BRA Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India.
Objective: There is dearth of clinical data from India regarding outcomes of umbilical cord blood transplant (UCBT). This study aimed to analyze the long-term outcomes in children who underwent UCBT at a single Indian center.
Methods: This retrospective study included patients who underwent UCBT between 2011 and 2024 in a tertiary care center in Northern India.
Bio Protoc
June 2025
Department of Biophysics, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Cancer-associated mesenchymal stem cells (Ca-MSCs), an integral part of the tumor microenvironment, play a major role in modulating tumor progression; they have been reported to progress as well as inhibit various cancers, including cervical cancer. To understand the exact role of Ca-MSCs in tumor modulation, it is necessary to have an optimized protocol for Ca-MSCs isolation. This work demonstrates the isolation and expansion of a primary culture of cervical cancer-associated MSCs (CCa-MSCs) from the biopsy sample of cervical cancer patients using the explant culture technique.
View Article and Find Full Text PDFZhongguo Shi Yan Xue Ye Xue Za Zhi
June 2025
Department of Clinical Laboratory Medicine, The 900th Hospital of Joint Logistics Support Force, PLA ,Fuzhou 350025, Fujian Province, China.
Objective: To understand clinical and laboratory characteristics of acute myeloid leukemia, myelodysplasia-related (AML-MR).
Methods: Blood sample of one patient with AML-MR admitted to our hospital in September 2021 was collected and synthetically analyzed by using techniques including complete blood cell count, peripheral blood and bone marrow cell morphology, bone marrow pathology and immunohistochemistry, hematology examination, flow cytometry (FCM), chromosome karyotype analysis and molecular pathology. The clinical and laboratory characteristics of AML-MR were analyzed and summarized according to the World Health Organization (WHO) standards.