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In demographic research, the accuracy of the reported ages in surveys and censuses is a persistently important issue. The common indices developed and used to examine the quality of age data are Whipple, Myers, Bachi's, modified Whipple, and the total modified Whipple's index. The most commonly used and simplest to compute index is the original Whipple's index proposed by George Chandler Whipple. It is a summary measure used to check age heaping on ages ending with digits 0 and 5. The other summary index is the total modified Whipple index by Spoorenberg. A robust modification is proposed for the total modified Whipple index. This modification, based on the method of the original Whipple index for all digits (0, 1, 2 … 9), is simple, robust, and easy to interpret. The proposed index is used to check the quality of age data from the Demographic and Health Survey data series of three countries (India, Pakistan, and Turkey). The original Whipple index only measures the preferences or avoidances of ages ending in digits 0 and 5. The existing summary index total modified Whipple index, based on modified Whipple indexes, covers all ages; however, results showed that the digit indexes for the terminal digits 1, 2, 3 and 4 have some added probability of being included. The newly proposed summary index, Robust Modified Whipple Index, is based on Rogers Whipple indexes, which display an equal probability for all ten digits i = 1,2,3…,9. In the application to the series of datasets, the proposed index is found better and more robust. The comparison of the results of the total modified Whipple index and proposed robust modified Whipple index concludes that the proposed modification is a more precise and robust to measure age misreporting by taking the effects of all terminal digits of reported ages. The proposed modification is suitable for the evaluation of the quality of self reported and interviewer recorded ages at the time of surveys and censuses.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12373282 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0330519 | PLOS |
PLoS One
August 2025
Laboratory of Demographic Data, Max Planck Institute for Demographic Research, Rostock, Mecklenburg, Germany.
In demographic research, the accuracy of the reported ages in surveys and censuses is a persistently important issue. The common indices developed and used to examine the quality of age data are Whipple, Myers, Bachi's, modified Whipple, and the total modified Whipple's index. The most commonly used and simplest to compute index is the original Whipple's index proposed by George Chandler Whipple.
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May 2025
Geriatrics, East Lancashire Hospitals NHS Trust, Blackburn, GBR.
Pancreatic adenocarcinoma remains a highly fatal cancer, especially when classified as borderline resectable, characterized by limited involvement of surrounding major blood vessels that challenges but does not absolutely preclude curative surgical resection. We report the case of a 65-year-old male with a history of smoking who presented with progressive, painless jaundice, pruritus, and weight loss over 15 months. Imaging revealed intrahepatic biliary dilation, a distal common bile duct stricture, and a mass in the pancreatic head with peripancreatic lymphadenopathy.
View Article and Find Full Text PDFCochrane Database Syst Rev
March 2025
Surgical and Translational Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Background: Resection of the head of the pancreas is most commonly done by a pancreaticoduodenectomy, known as a Whipple procedure. The most common indication for pancreaticoduodenectomy is malignancy, but can include benign tumours and chronic pancreatitis. Complete surgical resection, with negative margins, provides the best prospect of long-term survival.
View Article and Find Full Text PDFGenome Biol
February 2025
Therapeutic Innovation Center & the Verna Marrs McLean Department of Biochemistry & Molecular Pharmacology, Baylor College of Medicine, Houston, TX, USA.
Background: Small nucleolar RNAs (snoRNAs) are non-coding RNAs that function in ribosome and spliceosome biogenesis, primarily by guiding modifying enzymes to specific sites on ribosomal RNA (rRNA) and spliceosomal RNA (snRNA). However, many orphan snoRNAs remain uncharacterized, with unidentified or unvalidated targets, and studies on additional snoRNA-associated proteins are limited.
Results: We adapted an enhanced chimeric eCLIP approach to comprehensively profile snoRNA-target RNA interactions using both core and accessory snoRNA-binding proteins as baits.
Insect Mol Biol
August 2025
Bayer Crop Science, Chesterfield, Missouri, USA.
RNA-based bioinsecticides that comprise a dsRNA active ingredient and function by RNA interference (RNAi) are being commercialised as insecticidal traits in transgenic crops and as sprayable biopesticides. These RNAi insecticidal technologies are valuable alternatives to conventional chemical insecticides due to their efficacy, high degree of specificity and favourable human and environmental safety profiles. As with all pesticides, appropriate insect resistance management (IRM) programmes are required to mitigate the selection for resistance in target insect populations and extend product durability in the field.
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