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Objective: To investigate the application effect of personalized health management strategies based on the WeChat platform in improving the overall health status of patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD), aiming to provide scientific evidence for enhancing the health management of AECOPD patients.
Methods: From February 2024 to September 2024, a total of 120 AECOPD patients treated in the Comprehensive Ward of Respiratory and Critical Care Medicine at the Second People's Hospital of Fuyang City were selected. They were divided into an observation group and a control group, each consisting of 60 patients, using the random number table method. The control group received conventional care, while the observation group additionally utilized the WeChat platform for personalized health education, symptom monitoring guidance, patient-doctor interaction, and other interventions. Post-intervention comparisons were compared between the two groups regarding self-management ability scores, quality of life scores, readmission rates, and emergency visit frequencies.
Results: After the intervention, the self-management ability score of the observation group was significantly higher than that of the control group, with higher scores in symptom management, daily life management, emotional management, information management, and self-efficacy. Quality of life was also better in the observation group compared to the control group, particularly in physiological, psychological, sociocultural, and environmental aspects. The readmission rate was 8.33% (5/60) and emergency visits were 6.67% (4/60) in the observation group, both significantly lower than the control group's 21.67% (13/60) and 20.00% (12/60). Clinical outcomes showed 13.3% absolute risk reductions in both readmissions and emergency visits (NNT = 7.5 for both). Nursing satisfaction in the observation group reached 93.33%, significantly higher than 76.67% in the control group, with all differences being statistically significant (P < 0.05).
Conclusion: The auxiliary management model based on the WeChat platform effectively enhances the self-management capabilities of AECOPD patients, improves their quality of life, reduces hospital readmissions and emergency visits due to disease exacerbations, increases nursing satisfaction, optimizes medical resource allocation, and promotes long-term health management among patients, thus possessing substantial clinical promotion value.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12360646 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0330673 | PLOS |
Ann Surg Oncol
September 2025
Department of Thoracic Surgery, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian Province, China.
Background: RUNX3 acts as a tumor suppressor gene in non-small-cell lung cancer (NSCLC), yet its specific biological mechanism is still unclear. This study aimed to uncover tumor microenvironment (TME) changes in NSCLC with varying RUNX3 expression statuses through single-cell RNA sequencing.
Patients And Methods: In total, seven patients with NSCLC with detailed pathological data were involved, with three both paracancerous and cancerous tissue samples.
Clin Oral Investig
September 2025
Department of Periodontics, Saveetha Dental College, Saveetha Institute of Medical and Technology Sciences, SIMATS, Saveetha University, Chennai, Tamil Nadu, India.
Objectives: This study aims to assess periodontal and biochemical parameters and evaluate the salivary Protectin D1 levels in periodontitis patients with and without metabolic syndrome after non-surgical periodontal therapy.
Materials And Methods: Forty patients were categorized into two groups: 20 patients in Group P (systemically healthy patients with stage II/III grade B periodontitis) and 20 patients in Group P+MS (patients with stage II/III grade B periodontitis and metabolic syndrome). Parameters including age, gender, height, weight, body mass index, waist circumference, socio-economic status, oral hygiene index (OHI), modified gingival index (MGI), probing pocket depth, clinical attachment levels, fasting blood glucose, HDL-c, total triglycerides, and blood pressure were recorded.
J Egypt Natl Canc Inst
September 2025
National Cancer Institute of Cairo University, Giza, Egypt.
Objectives: To balance the extended functional urinary voiding and morbidity outcomes amid Ileal W and Y-shaped contrasted to spherical ileocoecal (IC) orthotopic bladders subsequent prostate-sparing radical cystectomy (PRC) versus standard radical cystoprostatectomy (RC).
Material And Methods: Two hundred eight male bladder cancer patients were grouped into 98 RC followed by 43-W, 31-Y, and 23-IC in comparison to 110 PRC followed by 35-W, 37-Y, and 38-IC. The functional voiding outcomes were determined by detailed patients' interview and urodynamic studies (UDS).
Discov Nano
September 2025
Department of Chemistry, A.S.P. College, Devrukh Dist, Ratnagiri, Maharashtra State, India.
Herein, ruthenium nanoparticles (RuNPs) were synthesized using Tridax procumbens leaf extract as a reducing and stabilizing agent. The synthesis was optimized by adjusting temperature, leaf extract concentration, and reaction time. The synthesized RuNPs were characterized using UV-visible, XRD, EDAX, FTIR spectroscopy, SEM, and TEM, revealing uniform size and morphology.
View Article and Find Full Text PDFJ Neurol
September 2025
Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.
Objective: To evaluate the clinical efficacy of tocilizumab, a interleukin-6 (IL-6) receptor blocker, for the treatment of acute necrotizing encephalopathy (ANE).
Methods: PubMed, Cochrane Library, Embase, and Web of Science were searched for systematic review based on PRISMA guidelines. ANE patients treated with and without tocilizumab were included.