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Testing and evaluation are essential for verifying the safety of the intended function (SOTIF) of autonomous driving systems (ADS), which focuses on estimating the system's functional boundaries through a limited set of tests to assess its safe operational range. To achieve this, a series of valuable safety-margin scenarios must be designed as test cases. However, scenario testing faces the dilemma of the curse of dimensionality and the requirements for test coverage. Consequently, the construction and selection of test cases become significant challenges. Moreover, due to the black-box nature of the system under test (SUT), surrogate models are often introduced during the scenario generation process, which can introduce model deviation relative to the actual system and potentially lead to ineffective test scenarios as well as incorrect estimation of system functional boundaries (SFB). To address these challenges, an efficient framework for generating high-dimensional safety-margin scenarios and tracking SFB of SUT is proposed, which utilizes a baseline surrogate model to generate a diverse and comprehensive library of safety-margin test scenarios through a multi-population genetic algorithm (MPGA). Additionally, a System Functional Boundary Tracking (SFBT) module is employed to compensate for the deviation between the baseline surrogate model and the actual SUT, thereby adaptively generalizing the library of critical scenarios to estimate its high-dimensional functional boundaries. This framework will potentially assist in the testing and validation of the Operational Design Domain (ODD) for ADS.
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http://dx.doi.org/10.1016/j.aap.2025.108156 | DOI Listing |
PLoS One
September 2025
Hunan Mingxiang Aviation Technology Co., Ltd., Changsha, Hunan, China.
Flexible spacecraft possess the ability to adapt to complex environments and use energy more efficiently, offering enhanced flexibility and stability in space missions, particularly in tasks with significant external disturbances such as deep space exploration and satellite attitude control. However, vibration suppression in flexible spacecraft remains a critical challenge. This study addresses the problem of vibration suppression in flexible spacecraft systems under external disturbances and input constraints.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Engineering and School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
Citizen science engages volunteers to contribute data to scientific projects, often through visual annotation tasks. Hearing based activities are rare and less well understood. Having high quality annotations of performed music structures is essential for reliable algorithmic analysis of recorded music with applications ranging from music information retrieval to music therapy.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
September 2025
Thyroid eye disease (TED) is a prevalent autoimmune orbital disorder that can severely impair visual function and significantly diminish patients' quality of life. In recent years, several studies have attempted to automate TED diagnosis using optical coherence tomography (OCT) images. However, existing approaches primarily rely on convolutional neural networks (CNNs) combined with attention mechanisms and are mostly trained using traditional cross-entropy loss.
View Article and Find Full Text PDFPlanta
September 2025
Department of Biology, University of Naples Federico II, Via Cinthia 26, 80126, Naples, Italy.
The first complete plastid genome of the critically endangered species Valeriana trinervis was sequenced, assembled and compared with other published Valeriana plastomes. In this study, we assembled the plastid genome of the critically endangered, endemic species Valeriana trinervis (= Centranthus trinervis) and compare it with all published plastomes of Valeriana. We found not only differences in the inverted repeats boundaries, in the type and abundance of repeats, but also similarities in codon usage and microsatellite numbers.
View Article and Find Full Text PDFJ Math Biol
September 2025
Department of Mathematics, University of Illinois Urbana-Champaign, Urbana, USA.
A fundamental question in the field of molecular computation is what computational tasks a biochemical system can carry out. In this work, we focus on the problem of finding the maximum likelihood estimate (MLE) for log-affine models. We revisit a construction due to Gopalkrishnan of a mass-action system with the MLE as its unique positive steady state, which is based on choosing a basis for the kernel of the design matrix of the model.
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