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Objective: To investigate the efficacy and safety of minimally invasive percutaneous nephrolithotomy (MPCNL) combined with ureteral access sheath in the treatment of complex kidney stones.
Methods: Seventy patients with complex kidney stones in the author's hospital from June 2022 to December 2023 were randomized. There were 35 cases of minimally invasive percutaneous nephrolithotomy combined with ureteral access sheath and 35 cases of minimally invasive percutaneous nephrolithotomy alone.
Results: Compared to the MPCNL group, the MPCNL + UAS group demonstrated a significantly shorter operative time (55.4 ± 9.2 min vs. 61.5 ± 12.8 min, = 0.027), significantly lower intraoperative renal pelvic pressure (9.15 ± 4.13 mmHg vs. 11.35 ± 4.21 mmHg, = 0.031), and a significantly lower incidence of postoperative Clavien complications ( < 0.05); however, there were no significant differences between the groups in postoperative creatinine change, stone clearance rate at 1 day postoperatively, or stone clearance rate at 30 days postoperatively ( > 0.05).
Conclusions: Minimally invasive percutaneous nephrolithotomy combined with ureteral access sheath is safe and effective in the treatment of complex kidney stones. Ureteral access sheath can significantly shorten the operation time of minimally invasive PCNL, keep the visual field clear, reduce the pressure of renal pelvis, and reduce the incidence of complications.
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http://dx.doi.org/10.3389/fsurg.2025.1557603 | DOI Listing |
Multimed Man Cardiothorac Surg
September 2025
Department of Cardiothoracic Surgery, St George’s Hospital, St George's University Hospitals NHS Foundation Trust, London, UK
Three-dimensional (3D) guided robotic-assisted thoracic surgery is increasingly recognized as a leading technique for undertaking the most complex pulmonary resections, providing high-definition 3D visualization, advanced instrument control and tremor-free tissue handling. Compared with open thoracotomy, the robotic platform offers reduced peri-operative complications, shorter hospital stays and faster patient recovery. Nevertheless, sublobar resections, such as segmentectomies, remain both anatomically intricate and technically challenging, particularly when resecting multiple segments, as in this left S1 and S2 segmentectomy.
View Article and Find Full Text PDFInt Urogynecol J
September 2025
Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, Magee-Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Introduction And Hypothesis: Aging may place patients at greater risk for adverse perioperative outcomes. We hypothesized that women undergoing minimally invasive (MIS) sacrocolpopexy aged ≥ 70 years are more likely to experience adverse events (AE) within 8 weeks of surgery.
Methods: We performed a secondary analysis of a retrospective study on perioperative adverse events in women ≥ 61 years old undergoing prolapse surgery at a single academic center from January 2016 to May 2023.
ACS Sens
September 2025
Department of Pharmacy, The People's Hospital of Guangxi Zhuang Autonomous Region & Guangxi Academy of Medical Sciences, Nanning, Guangxi 530021, China.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder primarily characterized by cognitive decline and behavioral impairments, typically manifesting in the elderly and presenile population. With the rapid global aging trend, early diagnosis and treatment of AD have become increasingly urgent research priorities. The primary pathological features of AD include excessive accumulation of β-amyloid (Aβ) plaques, the formation of neurofibrillary tangles, and neuronal loss.
View Article and Find Full Text PDFInt J Surg
September 2025
Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Objectives: To provide a bibliometric overview of the global research on the therapeutic applications of the suprachoroidal space (SCS) from 2000 to 2024.
Methods: Publications were retrieved from the Web of Science Core Collection using a defined search strategy. A total of 776 articles were analyzed for trends in publication volume, countries, institutions, authorship, journals, citations, and keywords.
Adv Mater
September 2025
Department of Minimally Invasive Interventional Radiology, The Second Affiliated Hospital &Guangzhou Institute of Cancer Research, The Affiliate Cancer Hospital &School of Biomedical Engineering, Guangzhou Medical University, Guangzhou, 510260, China.
Surgical resection remains the frontline intervention for cancer; however, postoperative tumor recurrence and wound infection remain critical unmet challenge in surgical oncology. Herein, an all-in-one nanowired hydrogel (V-Hydrogel) is developed through a facile one-step assembly employing enzyme-mimetic VO nanowires and bactericidal crosslinker THPS. The V-Hydrogel reserves the glutathione peroxidase-, peroxidase-, catalase-, and oxidase-mimetic enzymatic activities derived from vanadium oxide nanowires, thereby exhibiting efficient tumor-specific catalytic therapy.
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