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Background: Though there are a growing number of programs seeking to prevent violence against women and children, adolescent girls often fall into a gap between these approaches. This article focuses on the impact of a violence prevention program, Rethinking Power, on the lives and wellbeing girls and young women aged 10-23.
Methods: The study utilized a quasi-experimental, mixed-methods design. The results focus on data collected with girls and young women (N = 1,627) who were of adolescent age during program implementation. A difference-in-difference approach explored the impact of the program on key outcomes using cross-sectional data from three timepoints. A survey of girls' groups participants was also undertaken (N = 752) and qualitative data was collected with adolescents and community stakeholders (52 focus groups and 61 interviews). Regression was utilized to analyze girls' group data and thematic analysis to analyze qualitative data. Data for mixed methods analysis was brought together using a convergent approach.
Results: The results show girls and young women the intervention areas reported less experiences of physical or sexual IPV in the past 12 months over time (from 25.7% at baseline to 15.7% at endline) and reduced, though non-significant due to small samples, odds of experiencing IPV compared to the controls (OR: 0.78; p = .51). Qualitative data also showed changes in violence, acceptance of violence and gender attitudes. Girls and young women in the intervention area (rather than control) had more than twice the odds of reporting that they could choose who to be friends with (OR: 2.59; p = .047) and had greater odds of agreeing that girls should be allowed to socialize just as boys (OR: 3.87; p <.001) and that a man should not have the final word at home (OR: 1.94; p = .019). Participants in girls' groups saw improvements on indicators related to gender attitudes, acceptance of violence, self-esteem and agency.
Conclusions: While not all results are statistically significant due to small sample sizes, they suggest that girl-focused programming, alongside a wider community-change process, can improve the lives of adolescent girls.
Trial Registration: The full trial was retrospectively registered in ISRCTN (ISRCTN12311597) on April 4th, 2024.
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http://dx.doi.org/10.1186/s12889-025-24033-z | DOI Listing |
J Neurooncol
September 2025
Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada.
Purpose: Breast cancer (BC) is the most frequent cancer among women and the second leading cause of central nervous system (CNS) metastases. While the epidemiology of CNS metastases from BC has been well described, little is known about the treatment patterns and outcomes of young women < 40 years of age with BC that is metastatic to the CNS.
Methods: In this retrospective analysis, we identified patients with metastatic breast cancer (MBC) to the CNS who were treated at the Sunnybrook Odette Cancer Center, Toronto, Canada between 2008 and 2018.
Eur Child Adolesc Psychiatry
September 2025
Center of Clinical Investigations, APHP.Nord, INSERM CIC1426, Robert Debré University Hospital, Paris, France.
The COVID-19 pandemic significantly worsened mental health (MH) challenges among young people. We aimed to assess changes in mental health-related outpatient care before and after the onset of the pandemic. In this nationwide cross-sectional study, we retrieved visits to general practitioners (GP) resulting in the coding of a MH disorder and/or the prescribing of any psychotropic medication for children aged 6 to 17 years, from January 1, 2016 to May 31, 2022 in France.
View Article and Find Full Text PDFEur Radiol
September 2025
Department of Ultrasound, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Objectives: To evaluate the predictive role of carotid stiffening, quantified using ultrafast pulse wave velocity (ufPWV), for assessing cardiovascular risk in young populations with no or elevated cardiovascular risk factors (CVRFs).
Materials And Methods: This study enrolled 180 young, apparently healthy individuals who underwent ufPWV measurements. They were classified into three groups: the CVRF-free group (n = 60), comprising current non-smokers with untreated blood pressure < 140/90 mmHg, fasting blood glucose (FBG) < 7.
Persistent high-risk human papillomavirus (hHPV) infection, especially HPV-16, plays a central role in the development of high-grade squamous intraepithelial lesions (HSIL). This study aimed to evaluate the performance of co-testing (cytology and hHPV detection) in a real-world cohort of men who have sex with men (MSM) and transgender women (TW) living with HIV. We conducted a prospective study (2017-2023) at a tertiary care center in Spain.
View Article and Find Full Text PDFmBio
September 2025
Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Enteroinvasive bacterial pathogens are responsible for an enormous worldwide disease burden that critically affects the young and immunocompromised. is a gram-negative enteric pathogen closely related to the plague agent that colonizes intestinal tissues, induces the formation of pyogranulomas along the intestinal tract, and disseminates to systemic organs following oral infection of experimental rodents. Prior studies proposed that systemic tissues were colonized by a pool of intestinal replicating bacteria distinct from populations within Peyer's patches and mesenteric lymph nodes.
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