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Article Abstract
Background And Purpose: This study aims to examine the global, regional, and national burden of stroke in young adults from 1992 to 2021.
Method: We conducted a comprehensive assessment of stroke metrics among individuals aged 15-49 using data from the 2021 Global Burden of Disease (GBD) database, covering 204 countries at global, regional, and national levels. The metrics evaluated included age-standardized incidence rates (ASIR), death rates (ASDR), disability-adjusted life years (DALYs), average annual percentage changes (AAPCs), and joinpoint regression analysis.
Results: Between 1992 and 2021, the ASIR, ASDR, and DALYs for ischemic stroke (IS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH) among young adults globally decreased. The incidence, mortality, and DALYs for all three stroke types declined in both young females and males. In countries with low-middle and middle Socio-demographic Index (SDI), the ASIR for IS showed an upward trend, while the ASIR for ICH and SAH decreased across different SDI countries. Nationally, the incidence, death, and DALYs for all three types of stroke decreased in the vast majority of countries, with only a few countries showing an increased trend.
Conclusion: From 1992 to 2021, the overall trend in stroke burden among young adults was downward. However, in certain countries and regions, incidence, death, and DALYs related to stroke still rose. It is crucial for nations around the globe to adopt comprehensive, easily accessible, and cost-effective strategies aimed at improving stroke monitoring, prevention, emergency treatment, and rehabilitative care, ultimately alleviating the impact of stroke.
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| http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2025.108414 | DOI Listing |
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