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http://dx.doi.org/10.1007/s12519-025-00958-8 | DOI Listing |
J Epidemiol
September 2025
Department of Social Medicine, National Center for Child Health and Development.
BackgroundIn 2023, a collaborative UNICEF-WHO group introduced the concept of small vulnerable newborns (SVNs) to improve the identification of newborns at increased risk of adverse outcomes and to guide more effective preventive strategies. However, global data on the prevalence of SVNs remains scarce. This study aimed to examine secular trends in the prevalence of SVNs and their three subgroups, namely term small for gestational age (SGA), preterm SGA, and preterm non-SGA, in the Japanese population.
View Article and Find Full Text PDFClin Pharmacol Ther
September 2025
School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.
This cross-sectional study aims to demonstrate the impact of China's 2015 review and approval reform on the delays in market entry for novel geriatric drugs, as well as the capability of domestic innovation in developing geriatric drugs. We analyzed the novel geriatric drugs approved by the US Food and Drug Administration (FDA) between 2005 and 2024 to assess the drug lags in China by using the EU and Japan as comparators. During this period, the FDA approved a total of 183 novel drugs targeting geriatric diseases, of which 109 were also approved by the NMPA.
View Article and Find Full Text PDFActa Trop
September 2025
Department of Public Health, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium.
Congenital toxoplasmosis (CT) due to Toxoplasma gondii, an apicomplexan parasite, leads to significant sequelae in children, foetal losses and neonatal deaths worldwide. This study aimed to assess the burden of CT in Burundi for the year 2020. We used epidemiological and economic data collected in major hospitals in Burundi, the Ministry of Public Health in Burundi and international peer-reviewed literature to estimate the disability-adjusted life years (DALYs) and economic costs spent on prenatal consultations, diagnosis and treatment of toxoplasmosis for pregnant women.
View Article and Find Full Text PDFAm J Med
September 2025
Faculty of Medical and Health Sciences, Tel-Aviv University, Tel-Aviv, Israel; School of Medicine, Stanford University, Stanford, CA, USA. Electronic address:
Background: Recurrent hospitalizations present significant financial burdens and health risks. Poor communication and lack of personalized care are major contributors to preventable readmissions. This study examined whether brief, personal conversations between physicians and hospitalized -patients could reduce 1-week and 30-days post-discharge readmissions, and improve satisfaction.
View Article and Find Full Text PDFRespir Med
September 2025
Department of Public Health and Infectious Diseases, Pulmonology Unit, Policlinico Umberto I, "Sapienza" University of Rome, 00185 Rome, Italy.
Purpose: Asthma and obstructive sleep apnea (OSA) are two respiratory diseases that often may coexist, resulting in Alternative Overlap Syndrome (aOVS), which is still underestimated and underdiagnosed.
Objectives: This state-of-art review aims to describe the current evidence on aOVS, including its pathophysiology, clinical, functional and therapeutic implications. A secondary objective is to assess whether aOVS can be identified as a distinct endophenotype needing personalized diagnostic and therapeutic strategies.