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Stroke incidence is rising among working-age adults in high-income countries. Employers often lack knowledge and skills to support return-to-work post-stroke. In the United Kingdom, nearly 40% of stroke survivors stop working. Vocational rehabilitation is rarely accessible, and self-guided resources often lack tools to support practical application. This study developed a self-guided return-to-work toolkit for stroke survivors and employers. Steps 1-4 of the six-step Intervention Mapping approach were followed. Intervention goal, content, and design were informed by three online workshops with employers (n = 12) and meetings with an advisory group (n = 20), including stroke charity and trade union representatives, stroke survivors, healthcare professionals, and experts in human resources and vocational rehabilitation. Theory-based pretesting (task-based usability review, advisory group discussions) was shaped by prototype review with advisory group members, including employers (n = 4), stroke survivors (n = 7), and healthcare professionals (n = 4). Framework analysis was used to structure feedback related to acceptability, ease of use/learnability, accessibility, inclusivity, perceived usefulness, and technical or environmental issues. No personal data were analysed. The toolkit aims to empower stroke survivors and employers to plan and manage a sustainable return-to-work post-stroke. It exists as two Xerte eLearning packages, with accessibility features such as screen reader compatibility and keyboard navigation. The toolkit contains theory- and evidence-based content for a) stroke survivors and b) employers, and includes downloadable PDF tools. Stroke survivor-focused content provides guidance on identifying and disclosing support needs to employers. Employer-focused content guides employers in increasing and maintaining understanding of stroke survivors' work abilities, and implementing and monitoring tailored reasonable adjustments. Pretesting indicated the toolkit is comprehensive, empowering, and fosters open communication, offering key information and practical tools. Minor refinements and technical improvements were suggested. This toolkit addresses a gap in return-to-work guidance in the United Kingdom. Refinement, testing, and evaluation in real-world settings are needed.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327610 | PMC |
http://dx.doi.org/10.1371/journal.pdig.0000971 | DOI Listing |
CNS Drugs
September 2025
Global Health Neurology Lab, Sydney, NSW, 2150, Australia.
Acute ischemic stroke (AIS) remains a leading cause of mortality and long-term disability globally, with survivors at high risk of recurrent stroke, cardiovascular events, and post-stroke dementia. Statins, while widely used for their lipid-lowering effects, also possess pleiotropic properties, including anti-inflammatory, endothelial-stabilizing, and neuroprotective actions, which may offer added benefit in AIS management. This article synthesizes emerging evidence on statins' dual mechanisms of action and evaluates their role in reducing recurrence, improving survival, and mitigating cognitive decline.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Nursing Department, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Stroke is a severe neurological disorder that significantly impacts patients' recovery and quality of life. Stroke patients frequently experience sleep disorders, including difficulty initiating sleep, insomnia, vivid dreams, and sleep apnea. These disorders not only disrupt nighttime rest but also significantly affect stroke recovery and prognosis, increasing the risks of recurrence and mortality.
View Article and Find Full Text PDFBrain
September 2025
Center for Brain Plasticity and Recovery, Center for Aphasia Research and Rehabilitation, Departments of Neurology and Rehabilitation Medicine, Georgetown University Medical Center, Washington, DC, 20057 USA.
The role of the right hemisphere in aphasia recovery has been controversial since the 19th century. Imaging studies have sometimes found increased activation in right hemisphere regions homotopic to canonical left hemisphere language regions, but these results have been questioned due to small sample sizes, unreliable imaging tasks, and task performance confounds that affect right hemisphere activation levels even in neurologically healthy adults. Several principles of right hemisphere language recruitment in aphasia have been proposed based on these studies: that the right hemisphere is recruited primarily by individuals with severe left hemisphere damage, that transcallosal disinhibition results in recruitment of right hemisphere regions homotopic to the lesion, and that increased right hemisphere activation diminishes to baseline levels over time.
View Article and Find Full Text PDFFront Neurol
August 2025
The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Background: After stroke, upper limb dysfunction seriously affects patients' quality of life. The uncertain prognosis of patients poses a challenge for therapists in developing personalized rehabilitation programs. Electroencephalograph (EEG) power spectrum changes during rehabilitation training may have a predictive effect on the improvement of upper limb movement.
View Article and Find Full Text PDFAsian Nurs Res (Korean Soc Nurs Sci)
September 2025
Nursing and Health school, Zhengzhou University, Zhengzhou City, Henan Province, China. Electronic address:
Purpose: To identify and explore the latent categories of self-control and clarify the relationship between self-control and self-management of stroke survivors under different categories.
Methods: This cross-sectional study was conducted using a general information questionnaire, the Chinese version of the Dual-Mode Self-Control Scale, and the Stroke Self-Management Scale to measure sociodemographic data, self-control, and self-management. The questionnaires were administered face-to-face, and a convenience sampling method was used to collect the data.