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Article Abstract
The copper(I)-catalyzed silyl conjugate addition to α-substituted α,β-unsaturated --butanesulfinyl ketimines presents a facile approach for the synthesis of acyclic β,β-disubstituted enesulfinamides. By varying the ligand associated with the copper catalysts, it is feasible to selectively produce multisubstituted enesulfinamides with either ()- or ()-configuration, thereby facilitating their effective use in the stereoselective nucleophilic reactions to construct less accessible acyclic quaternary or tetrasubstituted stereocenters, encompassing both absolute configurations.
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