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Background: Additive manufacturing technology has revolutionized the medical field by enabling the production of customized implants with complex internal structures that enhance mechanical properties and biocompatibility. These intricate designs often result in exceedingly large 3D model files due to the high level of detail required. The substantial data volume poses significant file storage, transmission, and processing challenges. Traditional compression methods cannot encode complex models efficiently without compromising accuracy and compatibility. This study aims to develop a lightweight encoding strategy for 3D geometric files in medical additive manufacturing that significantly reduces file size while preserving data accuracy and compatibility with existing industry-standard formats.
Methods: We proposed a geometric relationship-based clustering method for the topological reconstruction of mesh models. The method involves non-uniform and multi-scale mesh simplification to retain critical features and reduce redundant data. By encoding these repetitive features only once, the encoding strategy enhances compression efficiency. We implemented compatible encoding schemes for the AMF (Additive Manufacturing File) and 3MF (3D Manufacturing Format) data formats, referred to as Lite AMF and Lite 3MF. Experiments on three medical implant models were conducted to evaluate the effectiveness of the proposed method.
Results: The proposed encoding strategy achieved significant file size reductions, with Lite AMF and Lite 3MF formats reducing file sizes by 81.99% and 91.34%, respectively, compared to the original formats. The compression algorithm effectively preserved the geometric characteristics of the models. The Hausdorff distance between the original and compressed models was less than 0.001 for all three models, indicating high fidelity and maintaining accuracy within the acceptable manufacturing tolerances of current medical additive manufacturing technologies.
Conclusion: The lightweight encoding strategy effectively reduces the file size of complex medical 3D models by over 80% while preserving data accuracy and compatibility with existing formats. By efficiently encoding repetitive structures and optimizing mesh data, the method enhances storage and transmission efficiency, addressing the challenges of large data volumes in medical additive manufacturing. The compatibility with standard AMF and 3MF formats ensures that the encoded models can be directly utilized in existing 3D printing software without modification.
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http://dx.doi.org/10.1186/s41205-025-00283-w | DOI Listing |
J Prosthodont
September 2025
Department of Reconstructive Dentistry and Gerodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.
Purpose: This study aimed to compare the dimensional and positional deviations of additively manufactured removable dies fabricated using two bio-based resins and one conventional dental cast resin, while also evaluating these outcomes over a 4-week period.
Materials And Methods: A right mandibular first molar preparation on a typodont was scanned to digitally design removable dies and hollow partial arch casts. Based on a priori power analysis, a total of 30 dies (n = 10) and three hollow casts (n = 1) were fabricated using additive manufacturing (AM) from three different dental cast resins: DentaMODEL (DM), FotoDent bio-based model (CB), and soy-based resin (SB).
Front Bioeng Biotechnol
August 2025
Department of Traditional Chinese Medicine Rehabilitation, Jiangbei Branch of The First Hospital Affiliated to Army Medical University (Third Military Medical University), Chongqing, China.
Background: Complex interbody fusion remains challenging, while traditional surgical instruments are not suitable for complex spinal deformities. Porous tantalum (Ta) has excellent osteogenic properties, but there is currently a lack of research on its application in cervical thoracic interbody fusion.
Objective: To introduce the application of selective electron beam melting (SEBM) 3D printing technology in customized porous Ta vertebral fusion implants and evaluate its mid-term clinical efficacy in complex cervical thoracic fusion surgery.
Accid Anal Prev
September 2025
Industrial and Manufacturing Systems Engineering Department, University of Michigan-Dearborn, 4901 Evergreen Rd, Dearborn, 48128, MI, USA; University of Michigan Transportation Research Institute, 2901 Baxter Rd, Ann Arbor, 48109, MI, USA. Electronic address:
Pedestrian injuries remain a public health concern, with child pedestrians being particularly vulnerable due to their unique physical and cognitive characteristics. This study presents a comprehensive analysis comparing injury severity patterns between child (≤14 years) and non-child (>14 years) pedestrians using Lasso logistic regression and advanced machine learning techniques, specifically Catboost with SHAP (SHapley Additive exPlanations) values to interpret the models. By analyzing six years of national crash data from the Crash Report Sampling System (CRSS) from 2016 to 2021, we identify significant factors influencing injury outcomes for both age groups.
View Article and Find Full Text PDFCrit Rev Anal Chem
September 2025
Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysore, India.
The miniaturization of separation platforms marks a transformative shift in analytical science, merging microfabrication, automation, and intelligent data integration to meet rising demands for portability, sustainability, and precision. This review critically synthesizes recent technological advances reshaping the field-from microinjection and preconcentration modules to compact, high-sensitivity detection systems including ultraviolet-visible (UV/Vis), fluorescence (FL), electrochemical detection (ECD), and mass spectrometry (MS). The integration of microcontrollers, AI-enhanced calibration routines, and IoT-enabled feedback loops has led to the rise of self-regulating analytical devices capable of real-time decision-making and autonomous operation.
View Article and Find Full Text PDFAdv Healthc Mater
September 2025
Smart Materials, NanoSYD, Mads Clausen Institute, University of Southern Denmark, Alsion 2, Sønderborg, DK-6400, Denmark.
This study presents a comprehensive framework combining Selective Laser Melting (SLM) of Titanium (Ti64) alloys, finite element simulation, and artificial intelligence (AI) to advance orthopedic implants' design and predictive evaluation. Dense Ti64 specimens are fabricated using ten distinct SLM parameter sets to explore the effects of volumetric energy density (VED) on mechanical behavior, porosity distribution, and microstructural integrity. Optimal VED ranges are identified to balance defect minimization and mechanical performance, with porosity levels strongly influencing tensile strength and Young's modulus.
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