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Biomimetic nano dressings have superior biological activity, biocompatibility, and stimuli-responsive properties compared with traditional wound dressings due to their biomimetic design integration and show great potential in wound management. This review summarizes the materials and techniques used to prepare current biomimetic nano dressings, focusing on biomimetic design strategies. Moreover, we explore the application of biomimetic nano dressings in treating wounds associated with infections, burns, diabetes, and postoperative skin cancer. This review provides new perspectives on the design of biomimetic nano dressings and highlights future research directions to further advance innovative wound treatment strategies.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12315539 | PMC |
http://dx.doi.org/10.1093/burnst/tkaf038 | DOI Listing |
Redox Biol
August 2025
Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, No.119 South 4th Ring Road West, Beijing, China; Chinese Glioma Genome Atlas Network (CGGA) and Asian Glioma Genome Atlas Network (AGGA), Beijing, China; Beijing Engineering Research Center of Target
Glioma patients will inevitably develop resistance to temozolomide (TMZ) leading to tumor recurrence. By comparing genomic differences between primary and recurrent glioma patients, Thioredoxin reductase 1 (TrxR1) was identified as a crucial role in TMZ resistance. Glioma cells elevate the expression level of TXNRD1 to against TMZ-induced reactive oxygen species (ROS), thereby conferring TMZ resistance.
View Article and Find Full Text PDFACS Nano
September 2025
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Nanoparticles bind to proteins in cells selectively and form a protein corona around them. However, the mechanisms of protein conformational changes underlying the interactions between nanoparticles and protein coronas remain poorly understood. In this study, we prepared small molecule self-assembled nanoparticles (Aloin NPs) as a research tool to investigate the allosteric mechanism of protein coronas.
View Article and Find Full Text PDFBiomater Adv
September 2025
Key Laboratory of Artificial Intelligence & Micro Nano Sensors, Shanxi Province, College of Integrated Circuits, Taiyuan University of Technology, Taiyuan, China; Key Lab of Advanced Transducers and Intelligent Control System of the Ministry of Education, Taiyuan University of Technology, Taiyuan, C
This study addresses critical technical challenges in fabricating functional pigmented skin models via 3D bioprinting through the synergistic integration of droplet-based deposition and precision motion control. A hybrid bioprinting strategy was developed to create multilayer biomimetic architectures: the dermal layer was fabricated through extrusion of gelatin methacryloyl-polyacrylamide (GelMA-PAM) composites, while the epidermal layer incorporated precisely patterned melanocyte-laden GelMA-PAM arrays deposited via microvalve technology, subsequently solidified and populated with keratinocytes. To enhance printing reliability, a fractional-order proportional-integral control system optimized through particle swarm optimization (PSO-FOPI) was implemented, significantly improving motor speed regulation and positioning accuracy.
View Article and Find Full Text PDFJ Biochem Mol Toxicol
September 2025
Department of Biology, SR.C., Islamic Azad University, Tehran, Iran.
Among cancers, liver cancer is the fourth leading cause of mortality worldwide and drawbacks of conventional approaches could not inhibit this cancer. Thus, an efficient folic acid (FA)-functionalized chitosan (CS)-poly lactic-co-glycolic acid (PLGA) nanocarrier was fabricated for delivery of sodium butyrate (NB) therapeutics to HepG2 liver cancer cells. The fabricated CS-NB-PLGA-FA nanocarrier was characterized by FT-IR, DLS, TEM, and TGA.
View Article and Find Full Text PDFFront Bioeng Biotechnol
August 2025
NHC Key Laboratory of Nuclear Technology Medical Transformation, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, China.
Cerebral ischemic stroke (CIS) is a severe cerebrovascular disease that poses numerous challenges in diagnosis and treatment, primarily attributed to blood-brain barrier (BBB) constraints and inherent drug targeting limitations. Biomimetic membrane nanotechnology, as an emerging therapeutic approach, offers a novel therapeutic strategy by emulating biological membrane structures and functions. This review comprehensively examines biomimetic nanomedicines (BMNPs) in CIS management, encompassing preparation methodologies, material characterization, and specific diagnostic/therapeutic applications.
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