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The capability to measure the state of a neutral atom is vital to an atom-based quantum network, for applications including distributed quantum computing and long-distance quantum communication. However, single neutral atoms suffer from low achievable photon scattering rate and shallow trapping potential, which limits the fidelity and speed of state readout process. Here, by coupling a single neutral atom with a high-finesse fiber-based Fabry-Pérot microcavity in the Purcell regime, we realize strong enhancement of the atomic photoemission rate and high overall system efficiency, which enables ultrafast and high-fidelity discrimination of bright and dark hyperfine states of the atom. The readout fidelity can reach 99.1(2)% within 200 ns and 99.985(8)% within 9 μs. Furthermore, we demonstrate that state preparation via optical pumping can be efficiently accelerated by a real-time decision protocol based on ultrafast state readout. This work demonstrates the potential to serve as a high-performance atom-photon interface and paves the way to the implementation of a practical atom-based quantum network.
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http://dx.doi.org/10.1103/PhysRevLett.134.240802 | DOI Listing |
Anal Chem
September 2025
Qilu University of Technology (Shandong Academy of Sciences), Shandong Analysis and Test Center, Jinan 250014, China.
Abnormal levels of trypsin in the human body can lead to various diseases, yet conventional detection methods often lack operational simplicity and real-time readout capabilities. This work presents a state-of-the-art metal organic framework (MOF) nanozyme-integrated liquid crystal (LC) sensor (MHN-LC sensor) and demonstrates the detection of trypsin as a proof of the concept. By rational engineering of the MOF-808 framework with Al and l-histidine coordination, a novel MOF nanozyme (MHis-NE) exhibiting exceptional acetylcholinesterase (AChE)-mimetic activity is successfully prepared.
View Article and Find Full Text PDFSci Adv
September 2025
Division of Nanomaterials and Chemistry, Hefei National Research Center for Physical Sciences at the Microscale, Department of Chemistry, University of Science and Technology of China, Hefei 230026 China.
Optical-enabled identification and interaction provide an integral link between the digital and physical realms. However, nowadays optic-encodings, predominantly reliant on light's intensity and wavelength, are hindered by environmental light interference and limited information capacity. The introduction of unusual polarization states, such as circular polarization-which is absent from ordinary surroundings-holds promise for higher-dimensional interaction.
View Article and Find Full Text PDFPLoS Biol
September 2025
Neuroscience Training Program, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America.
Early sensory experience can exert lasting perceptual consequences. For example, a brief period of auditory deprivation early in life can lead to persistent spatial hearing deficits. Some forms of hearing loss (i.
View Article and Find Full Text PDFAvian influenza viruses (AIVs) are zoonotic pathogens that pose an increasing global threat due to their potential for significant economic losses in agriculture, spillover into humans, and the risk of a pandemic should human-to-human transmission occur. These concerns underscore the need for rapid, sensitive and specific tools to detect and differentiate circulating AIV subtypes and clades. Current AIV diagnostic methods rely on specialized equipment and trained personnel, limiting their use in the field and in low-resource settings.
View Article and Find Full Text PDFMagn Reson Med
September 2025
School of Biomedical Engineering & State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University, Shanghai, China.
Purpose: To develop a rapid 2D free-running myocardial mapping technique that is robust to through-plane respiratory motion.
Methods: A free-running golden angle radial sequence consisting of encoding and self-navigated auto motion calibration (SNAC) was developed. The encoding adopted inversion recovery (IR) prepared interleaved multi-slice acquisition with optimized inter-slice gap to ensure a uniform excitation of the middle slice regardless of through-plane respiratory motion.