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Incorporating biomass (e.g., bacterial cellulose, BC) pressure-sensing structures into plantar monitoring technologies could effectively defend users against insecure wear and inaccurate detection, while their capability in sensing pressure continuously when subjected to large pressure is hindered by their natural two-dimensional structure. Here, we present a microbial engineering strategy for fabricating hierarchical fully biomass pressure sensors (HFBPSs) with sufficient sensing capabilities and good structural stability for plantar pressure detection. Particularly, the incorporation of the biobased material loofah enables HFBPS to adopt a hierarchical structure from micro- and nanostructured sensing networks, allowing for dynamic changes in the series-parallel configuration of the circuit under large pressure. This innovative structure design breaks the bottleneck of low operating range encountered by traditional rigid two-dimensional BC pressure sensors, ensuring the HFBPS with ultrahigh sensitivity (2.82 kPa) and wide detection range (0-600 kPa). In addition to stably monitoring gait motions, the HFBPS integrated into smart insoles can recognize nonstandard Tai Chi movements. Our HFBPS with exceptional pressure-sensing performance provides significant impact on the future development of smart insoles for plantar monitoring.
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http://dx.doi.org/10.1021/acssensors.5c01823 | DOI Listing |
Front Bioeng Biotechnol
August 2025
Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Electroactive polymer (EAP) artificial muscles are gaining attention in robotic control technologies. Among them, the development of self-sensing actuators that integrate sensing mechanisms within artificial muscles is highly anticipated. This study aimed to evaluate the accuracy and precision of the sensing capabilities of the e-Rubber (eR), an artificial muscle developed by Toyoda Gosei Co.
View Article and Find Full Text PDFAdv Sci (Weinh)
September 2025
Department of Orthodontics, National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing Key Laboratory of Digital Stomatology, NHC Key Laboratory of Digital Stomatology, NMPA Key
Clear aligners offer aesthetic and comfort advantages in orthodontics, yet their ability to deliver effective forces relies heavily on empirical judgment or large-scale optical scanning, lacking real-time quantitative evaluation. Integrating pressure sensors into aligners is a promising solution, but challenges in miniaturization, multi-dimensional sensing, measurement accuracy, and biocompatibility hinder clinical application. Here, an all-in-one Orthodontic Force Acquisition System (OFAS) is presented that enables real-time, 3D force monitoring using a cross-shaped iontronic sensing array and an origami-inspired, wireless battery-free readout circuit miniaturized for single-tooth placement.
View Article and Find Full Text PDFCell Physiol Biochem
August 2025
Departamento de Procesos Químicos, Alimentos y Biotecnología. Facultad de Ingeniería y Ciencias Aplicadas. Universidad Técnica de Manabí, Portoviejo, Ecuador.
Background/aims: The quantification of amino acids in the dairy industry is necessary for quality control and for the formulation of functional foods. Thus, the development of enzymatic biosensors requires a detailed study of enzyme kinetics. Parameters such as KM and Vmax are necessary to optimize the sensitivity and specificity of the biosensor.
View Article and Find Full Text PDFJ Physiol
September 2025
Instituto de Ciencias Biomédicas, Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Santiago, Chile.
Cardiorespiratory responses to physical exercise are expected to meet the organism's metabolic demands. As carotid body (CB) glomus cells have been proposed as metabolic sensors, we sought to determine their contribution to peak oxygen uptake ( ) during exercise in rats. Adult male Wistar Kyoto rats underwent bilateral co-injection of two adeno-associated viruses (AAVs) at the CB bifurcation (AVV-TH-Cre-SV40 and AVV-hSyn-DREADD(Gi)-mCherry).
View Article and Find Full Text PDFIEEE J Biomed Health Inform
September 2025
Understanding foot kinetics is fundamental to analyzing human locomotion, offering critical insights into mechanical loads exerted on the feet. While vertical ground reaction force (vGRF) is widely used in biomechanics research, comprehensive 3D kinetic measurements, including ground reaction force (GRF), ground reaction moment (GRM), and center of pressure (CoP) along the anterior-posterior and medial-lateral axes, provide deeper insights for various applications. Smart insoles, though portable, cost-effective, and user-friendly, primarily capture vGRF and often generate lower-quality data than force plates and instrumented treadmills.
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