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Objectives: The ultimate aim of this study is to use multi-detector computed tomography (MDCT), which allows data to be constructed in three dimensions, to create reconstructed face images with low creator dependence and to be able to identify individuals in a short time. To this end, a 3D model was created as a basic study in this case, and each point on the midline was measured to identify areas of high distortion.
Methods: As a basic study of digital facial reconstruction, digital reconstruction of the soft tissue thickness of the face was measured using results from computed tomography of 15 male Japanese patients (five patients each for three body types: thin, standard, and obese) who visited the university hospital.
Results: The measurements of soft tissue thickness taken at 1-mm intervals downward in the lower part of the maxilla and at 1-mm intervals upward in the lower part of the mandible converged on the average to similar graphs, even though there were large individual differences and even though body sizes differed. Correlation coefficients between measured and average values of the materials were 0.94 overall, 0.91 for the upper maxilla, -0.55 for the lower maxilla, and 0.76 for the lower mandible, indicating distortion in the subnasal and upper and lower lip areas within the range of soft tissue reconstruction.
Conclusions: In this experiment, distortion was observed in the subnasal and upper and lower lip areas when soft tissues were reconstructed on the computer. Facial skin around the lip area represents the most strongly variable area of the face and requires careful attention during reconstruction.
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http://dx.doi.org/10.1007/s11282-025-00845-y | DOI Listing |
J Am Acad Orthop Surg
September 2025
From the Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY (Neitzke, O'Donnell, Buchalter, Chandi, Westrich, and Gausden), the Department of Orthopedic Surgery, University of Wisconsin-Madison, Madison, WI (O'Donnell), and Somers Orthopaedic Surgery & Sports Medicine Group
Introduction: Developmental dysplasia of the hip (DDH) poses challenges for component positioning during total hip arthroplasty (THA) secondary to abnormal bone morphology, soft-tissue contractures, and hip center migration. The objective of this study was to evaluate the radiographic and clinical outcomes of THA for DDH performed with robotic assistance versus manual (M) technique.
Methods: A retrospective review identified 115 patients with Crowe II to IV dysplasia undergoing primary THA at a single institution from 2016 to 2022.
Electroporation is a promising technology utilizing electrical pulses for macromolecule delivery and soft-tissue ablation, with applications that include next-generation prophylactics and the treatment of genetic diseases such as cancer. This study demonstrates a high-throughput capable 3D tissue culture model for quantification of the reversible and irreversible electroporation thresholds for a given electroporation protocol. By using a non-uniform electric field and analyzing the spatial distribution of transfected cells, both reversible and irreversible thresholds can be identified within a single sample, increasing the efficiency at which electroporation protocols can be characterized, especially for in vivo translation.
View Article and Find Full Text PDFJ Craniofac Surg
September 2025
Division of Plastic Surgery, Department of Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Facial feminization surgery (FFS) reshapes masculine facial attributes to align with feminine norms, yet normative anthropometric data for Asian populations remain sparse. We therefore quantified sex-related 3-dimensional (3D) facial metrics in healthy Asian adults to delineate dimorphic benchmarks for surgical planning. We prospectively recruited 40 healthy Asian adults (20 males, 20 females; age 18 to 45 years, mean 28.
View Article and Find Full Text PDFACS Nano
September 2025
Department of Electrical and Computer Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Vagus nerve stimulation (VNS) is a promising therapy for neurological and inflammatory disorders across multiple organ systems. However, conventional rigid interfaces fail to accommodate dynamic mechanical environments, leading to mechanical mismatches, tissue irritation, and unstable long-term interfaces. Although soft neural interfaces address these limitations, maintaining mechanical durability and stable electrical performance remains challenging.
View Article and Find Full Text PDF