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Background: Wireless Capsule Endoscopy (WCE) is one of the most advanced medical instruments, which can be used for non-invasive imaging detection of the digestive tract by patients taking microcapsules orally. This advanced technology enables medical professionals to evaluate the abnormal situations in the gastrointestinal tract efficiently, analyse the potential problems strictly, discuss the diagnosis and evaluation comprehensively, and make well-founded treatment decisions.
Methods: A scoping review was undertaken, gathering the most relevant sources, utilising a detailed literature search of medical and academic databases including EMBASE, PubMed, Cochrane, IEEE, Google Scholar, and the Google search engine.
Results: Of the 39 articles reviewed, 12 focused on the mechanical structure of WCE, 17 on intestinal lesion detection, and 10 on intestinal 3D reconstruction techniques. We conducted a thorough analysis of the active mechanical structures specifically designed to meet physiological demands and adapt to the dynamic gastrointestinal environment. Furthermore, we performed a comprehensive comparison and evaluation of various detection algorithms, discussing the characteristics of relevant datasets that significantly impact the diagnostic performance of WCE technologies. Lastly, we reviewed the current state and progress of 3D reconstruction techniques.
Conclusions: WCE can greatly improve the defects of current gastrointestinal examination technology, reduce patient pain, and enrich medical means. However, a large number of software and hardware problems need to be solved before being applied to clinical practice.
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http://dx.doi.org/10.1002/rcs.70094 | DOI Listing |
Prog Mol Biol Transl Sci
September 2025
School of Forensic Science, National Forensic Sciences University, Gandhinagar, Gujarat, India.
Ingestible biosensors are a mix of advanced biomedical engineering, digital health and precision pharmacotherapy. These miniaturised electronic devices are encapsulated in biocompatible materials, which operate within gastrointestinal (GI) tract. This enables real-time monitoring of pharmacological and physiological parameters.
View Article and Find Full Text PDFJ Biomed Phys Eng
August 2025
Department of Biomedical Systems & Medical Physics, Tehran University of Medical Sciences, Tehran, Iran.
Background: Wireless Capsule Endoscopy (WCE) is the gold standard for painless and sedation-free visualization of the Gastrointestinal (GI) tract. However, reviewing WCE video files, which often exceed 60,000 frames, can be labor-intensive and may result in overlooking critical frames. A proficient diagnostic system should offer gastroenterologists high sensitivity and Negative Predictive Value (NPV) to enhance diagnostic accuracy.
View Article and Find Full Text PDFSci Rep
September 2025
Department of ICT Convergence, Soonchunhyang University, Asan, 31538, Republic of Korea.
Worldwide, cancer is one of the leading causes of death in humans. Interobserver variability and specialized experience are key factors in diagnosing gastrointestinal tract (GIT) abnormalities using endoscopic procedures. Due to this diversity, small lesions may go unnoticed, leading to a delay in early diagnosis.
View Article and Find Full Text PDFDiagnostics (Basel)
August 2025
Department of Electrical and Electronics Engineering, Karamanoglu Mehmetbey University, Karaman 70100, Türkiye.
Gastrointestinal (GI) disorders present significant healthcare challenges, requiring rapid, accurate, and effective diagnostic methods to improve treatment outcomes and prevent complications. Wireless capsule endoscopy (WCE) is an effective tool for diagnosing GI abnormalities; however, precisely identifying diverse lesions with similar visual patterns remains difficult. Many existing computer-aided diagnostic (CAD) systems rely on manually crafted features or single deep learning (DL) models, which often fail to capture the complex and varied characteristics of GI diseases.
View Article and Find Full Text PDFFront Oncol
August 2025
Department of Neurosurgery, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Background: Cavernous lymphangioma represents a common lesion of the lymphatic system, yet it is rarely encountered in the small intestine. The diagnosis of small intestinal cavernous lymphangioma poses significant clinical challenges. This case report presents the optimal diagnostic and therapeutic management of pediatric small intestinal cavernous lymphangioma.
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