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This study investigated the application effect of lean management in the treatment of acute stroke in medical laboratories and evaluated the impact on laboratory turnaround time (TAT) and operator satisfaction. In this study, 287 patients with acute stroke were selected from the Second People's Hospital of Hunan Province and divided into a control group (129 cases, before lean management) and an experimental group (158 cases, after lean management). Lean management measures included establishing fast transfer channels, information management, optimisation of the centrifuge configuration, priority management, personnel training, use of the 6 S method, and visual management to optimise the process. The effects of lean management were evaluated by comparing the TAT of key inspection items using an operator satisfaction questionnaire. Lean management shortened the TAT for coagulation (21-18 min) and biochemical (33-29 min) tests (P = 0.000). Laboratory operators reported that lean management positively affects the overall performance of the laboratory. The application of lean management in medical laboratories can effectively improve the treatment efficiency of patients with acute stroke, shorten the TAT of key detection items, and provide high satisfaction among laboratory personnel.
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http://dx.doi.org/10.1038/s41598-025-12955-y | DOI Listing |
Osteoarthritis Cartilage
September 2025
Clinical Epidemiology Unit, Orthopaedics, Department of Clinical Sciences Lund, Lund University, Lund, Sweden. Electronic address:
Aim: To summarise key epidemiological and therapeutic research on osteoarthritis (OA) published between April 2024 and March 2025.
Methods: A narrative review was conducted using the MEDLINE database, focusing on English-language studies involving human participants published between April 1, 2024 and March 31, 2025. Eligible studies included observational longitudinal studies, systematic reviews, meta-analyses, and phase II-IV randomised controlled trials (RCTs) examining OA treatment and epidemiology.
Front Vet Sci
August 2025
Faculty of Veterinary Science, University of Sydney, Camden, NSW, Australia.
Introduction: Metabolic alkalosis induced by prepartum diet cations impairs Ca homeostasis in the periparturient cow. Adding anions to prepartum diets reduces blood pH improving periparturient Ca homeostasis. Urine pH generally reflects blood pH and is practical to measure on farm.
View Article and Find Full Text PDFJ Health Organ Manag
September 2025
UFF , Niteroi, Brazil.
Purpose: Propose an integrated approach of Lean Healthcare (LH) with Data Envelopment Analysis (DEA), establishing best practices for waste reduction and process improvement along with hospital efficiency.
Design/methodology/approach: The study proposes a two-stage approach integrating LH and DEA to enhance hospital efficiency. The first stage identifies efficient hospitals post-LH implementation and projects efficiency for inefficient ones using ideal projections.
Dermatol Ther (Heidelb)
September 2025
Dermatology Clinic, University Hospital Company Polyclinic "G. Rodolico, San Marco", Catania, Italy.
Introduction: Psoriasis (PsO) is a common inflammatory dermatological condition with a substantial negative impact on patient quality of life. Several biological agents are available for the treatment of PsO, and clinicians and patients must consider various factors when deciding on the most appropriate biological agent.
Methods: Here, we report a set of consensus statements developed by an Italian PsO advisory board on use of the anti-interleukin-17A biological secukinumab in routine clinical practice.
Medicine (Baltimore)
August 2025
Department of Endocrinology, Jiangxi Provincial Children's Hospital, Jiangxi, China.
This study evaluated the effects of recombinant human growth hormone (rhGH) on bone mineral density (BMD) and body composition in Chinese adolescents with transitional growth hormone deficiency (TGHD). A prospective cohort study was conducted from September 2021 to September 2024, involving 37 TGHD patients (15-18 years) and 7 healthy controls. After a 3-month rhGH washout, 9 confirmed TGHD patients (diagnosed per 2019 AACE criteria) were stratified into treatment (n = 4, rhGH continuation) and non-treatment (n = 5) groups.
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