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To compare the perioperative outcomes between the MP1000 and da Vinci Xi surgical systems in robot-assisted partial nephrectomy (RAPN) and examine the MP1000 learning curve. In this prospective single-center study, 90 patients undergoing RAPN were equally allocated to the MP1000 ( = 45) or da Vinci Xi ( = 45) groups. Perioperative outcomes were analyzed, and the learning curve was assessed for MP1000 group operative times. All procedures were completed without positive surgical margins. Significant discrepancies were observed in operation time, docking time, and estimated blood loss ( < 0.05). Postoperative estimated glomerular filtration rate (day 2), length of stay, and complication rate showed no significant differences. The cumulative sum curve was best fit by the equation , and , with peak at case 13, and is subsequently delineated into a learning group (1-13 cases) and a skilled group (14-45 cases). The two groups exhibited comparable baseline characteristics. The MP1000 system is effective for partial nephrectomies, with all cases completed effectively. Meanwhile, surgeons with prior experience using the da Vinci Xi system achieve proficiency with the MP1000 after 13 procedures.
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http://dx.doi.org/10.1089/end.2024.0870 | DOI Listing |
Obes Surg
September 2025
Clinique Mutualiste de Pessac, Pessac, France.
Background: Preoperative treatment with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) before bariatric surgery has not been studied. Therefore, we investigated the impact of neoadjuvant treatment with GLP-1 RAs on weight loss and postoperative outcomes in patients who underwent sleeve gastrectomy for severe obesity.
Method: A retrospective single-center study was conducted between January 2022 and December 2023.
Ren Fail
December 2025
Department of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, China.
This study aimed to develop a predictive model and construct a graded nomogram to estimate the risk of severe acute kidney injury (AKI) in patients without preexisting kidney dysfunction undergoing liver transplantation (LT). Patients undergoing LT between January 2022 and June 2023 were prospectively screened. Severe AKI was defined as Kidney Disease: Improving Global Outcomes stage 3.
View Article and Find Full Text PDFJ Immunother Cancer
September 2025
CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing, China
Neoadjuvant immunochemotherapy (nICT) has demonstrated significant potential in improving pathological response rates and survival outcomes for patients with locally advanced esophageal squamous cell carcinoma (ESCC). However, substantial interindividual variability in therapeutic outcomes highlights the urgent need for more precise predictive tools to guide clinical decision-making. Traditional biomarkers remain limited in both predictive performance and clinical feasibility.
View Article and Find Full Text PDFEur J Vasc Endovasc Surg
September 2025
Department of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden.
Objective: To examine trends in treatment strategies and perioperative outcomes for intact and ruptured complex abdominal aortic aneurysms (cAAA) across seven countries.
Design: Multinational, registry-based observational study within the VASCUNET framework.
Methods: This study used aggregated data from vascular registries in Australia, Denmark, Finland, New Zealand, Portugal, Sweden, and Switzerland.
Adv Med Sci
September 2025
Department of Biology, Lund University, Lund, Sweden.
Purpose: Ovarian cancer ranks as a gynecological malignancy with poor prognosis, specifically if detected late. Primary treatment includes cytoreductive surgery and adjuvant chemotherapy with curative intent. Local anesthetics (LA) administered in the perioperative period may potentially impact patient outcome by several mechanisms.
View Article and Find Full Text PDF