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Phthalic acid esters (PAEs), a class of synthetic semi-volatile organic compounds, are extensively incorporated into decorative materials. However, their specific occurrence, migration behaviors, and environmental impact on these materials-which comprise the largest surface areas in residential settings-remain insufficiently understood. This study investigated the distribution, emission dynamics, and environmental burdens of PAEs in flooring commonly used in Chinese households. The results showed that PAEs are widespread in flooring, with total concentrations ranging from 1220 to 166,000 ng/g (14,100 ng/g, median value). Solid wood flooring (55,900 ng/g) exhibited significantly higher PAE levels compared to engineered flooring (22,600 ng/g) and laminate flooring (4000 ng/g) ( < 0.05). Migration experiments revealed that solid wood flooring tended to continuously release PAEs, laminate flooring showed a pronounced capacity for PAE absorption, and engineered flooring exhibited both release and absorption behaviors. The initial PAE concentration is the dominant factor influencing migration rates, while the flooring type and substrate density also contribute to varying degrees. The estimated environmental burdens of PAEs resulting from flooring in newly renovated Chinese households ranged from 3.63 × 10 ng to 3.45 × 10 ng, with a median value of 1.23 × 10 ng. Households in the eastern and southwestern regions exhibited the highest PAE burdens, while the southern region showed the lowest. Socioeconomic factors such as residential floor area, number of rooms, household income, and renovation budget significantly influenced the environmental burden of PAEs derived from flooring.
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http://dx.doi.org/10.3390/toxics13070517 | DOI Listing |
J Nephrol
September 2025
Department of Psychology, Institute of Psychiatry, Psychology & Neuroscience, Health Psychology Section, King's College London, 5th Floor Bermondsey Wing, Guy's Campus, London Bridge, London, SE1 9RT, UK.
Background: Depression and anxiety are common in chronic kidney disease (CKD) and worsen clinical outcomes. Psycho-behavioural interventions offer a promising, non-pharmacological approach. However, most evidence comes from people with kidney failure with distinct treatment needs, limiting relevance to earlier stages of CKD, where timely support may enhance self-management and slow progression.
View Article and Find Full Text PDFInfection
September 2025
The Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Inge Lehmanns Vej 7, 16th floor, Copenhagen, 2100, Denmark.
Purpose: Infective endocarditis (IE) has been associated with severe outcomes when complicated by diabetes mellitus (DM). We aimed to report characteristics, microbial etiology, and mortality for patients with IE stratified by DM from a nationwide cohort.
Methods: We used Danish registries, and patients with first-time IE (2010-2020) were stratified by DM.
Skeletal Radiol
September 2025
Department of Radiology, Hospital do Coração (HCor), Rua Desembargador Eliseu Guilherme, 53, 7th floor. CEP, São Paulo, SP, 04004-03, Brazil.
Atypical proximal tibial fractures in adolescents are rare, particularly when linked to hormonal therapy for short stature. This case series reports the clinical and imaging features of atypical proximal tibial and distal femoral physeal fractures in male adolescents undergoing combined growth hormone (GH) and aromatase inhibitor (AI) therapy for idiopathic short stature. We report three cases of skeletally immature male adolescents (ages 12-16) treated with GH and anastrozole who presented with acute leg pain following low-energy trauma during soccer.
View Article and Find Full Text PDFJ Pathol Inform
November 2025
Pathology and Laboratory Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.
Evaluation of tumor infiltrating lymphocytes as recommended by current guidelines is largely based on stromal regions within the tumor. In the context of epithelial malignancies, the epithelial region and the epithelial-stromal interface are not assessed, because of technical difficulties in manually discerning lymphocytes when admixed with epithelial tumor cells. The inability to quantify immune cells in epithelial-associated areas may negatively impact evaluation of patient response to immune checkpoint therapies.
View Article and Find Full Text PDFPeriodontol 2000
September 2025
Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.
Transcrestal sinus augmentation has emerged as a minimally invasive alternative to lateral window techniques for vertical bone augmentation in the edentulous maxilla. Since its early introduction and modification over the last several decades, this technique has demonstrated predictable outcomes for implant placement in regions with limited bone height. This narrative review examines the current understanding and evolution of transcrestal sinus floor elevation (TSFE), focusing on factors related to long-term stability.
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