Correlation Between Anxiety, Depression, and Self-Perceived Hoarseness: A Systematic Review of the Literature.

J Voice

Department of Surgery, University of Mons, Mons, Belgium; Department of Otolaryngology-Head and Neck Surgery, Foch Hospital, School of Medicine, University Paris Saclay, Paris, France.

Published: July 2025


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Article Abstract

Objective: This review aims to evaluate the correlation between anxiety, depression, and self-perceived hoarseness in patients with dysphonia.

Study Design: Systematic review.

Methods: A systematic search of Medline, PubMed, and Cochrane databases was performed. Studies focusing on the relationship between anxiety, depression, and self-reported voice measures in dysphonic patients were included, while duplicates, incomplete data, animal studies, and reviews were excluded, following Preferred Reporting Items for Systematic Reviews and Meta Analyses guidelines.

Results: Of the 416 articles identified, 24 papers were reviewed. Eleven studies met the inclusion criteria and were included. Most studies used the Voice Handicap Index (VHI), VHI-10, and the Hospital Anxiety and Depression Scale as assessment tools. The studies demonstrated a positive correlation of varying degrees between anxiety, depression, and self-perceived hoarseness, except for patients with spasmodic dysphonia in one study.

Conclusion: This review highlights significant positive correlation between anxiety, depression, and self-perceived hoarseness, emphasizing the importance of early identification and treatment of mental health issues to improve patient outcomes.

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http://dx.doi.org/10.1016/j.jvoice.2025.06.007DOI Listing

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