Nitric Oxide Regulates Multiple Signal Pathways in Plants via Protein -Nitrosylation.

Curr Issues Mol Biol

Key Laboratory of Molecular and Cellular Biology of Ministry of Education, College of Life Sciences, Hebei Normal University, Shijiazhuang 050024, China.

Published: May 2025


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Article Abstract

Nitric oxide (NO) can perform its physiological role through protein -nitrosylation, a redox-based post-translational modification (PTM). This review details the specific molecular mechanisms and current detection technologies of -nitrosylation. It also comprehensively synthesizes emerging evidence of -nitrosylation roles in plant biological processes, including growth and development, immune signaling, stress responses and symbiotic nitrogen fixation. Furthermore, the review analyzes research progress on the crosstalk between -nitrosylation and other protein PTMs. Finally, unresolved issues such as the spatio-temporal resolution of SNO-proteome mapping and standardized protocols for reproducibility are pointed out. In summary, this work proposes a roadmap for future research.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12192061PMC
http://dx.doi.org/10.3390/cimb47060407DOI Listing

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