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Introduction: Undocumented migrants in Latin America face life-threatening conditions during irregular border crossings, yet their mortality remains under-documented and structurally invisible in public health research. This study analyzes migrant deaths and assesses the methodological limitations in estimating mortality for those populations.
Methods: Cross-sectional data were drawn from the Missing Migrants Project, covering deaths and disappearances of Latin American migrants within the region from 2014 to 2022. The final sample included 1,817 documented fatalities with complete data on year and origin. The study analyzed spatial and temporal trends by region, migration route, country of origin, and cause of death. Data were grouped into three periods and tested for distributional differences using chi-square tests.
Results: From 1,817 deaths, nearly half occurred between 2020 and 2022. Regional patterns shifted over time, with a rising share of deaths in South America, particularly along the Darién Gap. Venezuelan and Haitian migrants accounted for the largest increases in deaths in recent years. Causes varied by route: drowning predominated in maritime crossings, while environmental exposure and violence were prevalent in jungle and borderland routes. Documentation improved over time, yet a large share of deaths remained unattributed to specific routes or causes.
Conclusions: Undocumented migrant mortality in Latin America is shaped by structural violence, fragile transit infrastructures, and inadequate data systems. Conventional demographic tools fail to capture these patterns due to missing denominators and fluid migration flows. Addressing these deaths requires new frameworks grounded in human rights, improved data systems, and expanded access to safe migration pathways.
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http://dx.doi.org/10.1016/j.jeph.2025.203125 | DOI Listing |
Future Oncol
September 2025
Department of General Surgery, Institute of General Surgery, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou University, Yangzhou, China.
Immune checkpoint therapy has demonstrated significant potential in the treatment of various solid tumors. Among these, tumor-induced immunosuppression mediated by programmed cell death protein 1 (PD-1) represents a critical checkpoint. PD-1/programmed death-ligand 1 (PD-L1) inhibitors have been proven to exhibit substantial efficacy in solid tumors such as melanoma and bladder cancer.
View Article and Find Full Text PDFHypertension
September 2025
Department of Hypertension, Center for Epidemiological Studies and Clinical Trials, the Shanghai Institute of Hypertension, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China (J.W.).
Background: The association between season of screening blood pressure (BP) measurement and adverse outcomes has not been examined among populations without prior physician-diagnosed hypertension. We aimed to investigate the association between the season of screening clinic BP measurement and the risk of all-cause mortality.
Methods: This was a prospective cohort study, and data were analyzed from an ongoing community hypertension screening program in Shanghai between 2018 and 2024.
Death Stud
September 2025
Department of Psychology, University of Liverpool, Liverpool, UK.
Although there is considerable research into the impact of homicide on surviving family members, research is limited on subjective experiences of those who lost a parent due to homicide during childhood. Through interpretative phenomenological analysis, we conducted and analyzed in-depth semi-structured interviews, to explore lived experiences and perspectives of post-traumatic growth with adults who lost a parent due to homicide as a child. We developed five group experiential themes: 1.
View Article and Find Full Text PDFOpen Res Eur
September 2025
Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, 1870, Denmark.
Background: Innovative antibiotic discovery strategies are urgently needed to successfully combat infections caused by multi-drug-resistant bacteria.
Methods: We employed a direct screening approach to identify compounds with antimicrobial and antimicrobial helper-drug activity against Gram-positive and Gram-negative bacteria. We used this platform in two different strains of methicillin-resistant (MRSA) and aminoglycoside-resistant strains of to screen for antimicrobials compounds, which potentiate the activity of aminoglycoside antibiotics.
Epidemiol Psychiatr Sci
September 2025
Unit of Psychiatry, Department of Public Health and Medicinal Administration, Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Taipa, MO, China.
Aims: Loneliness is a common public health concern, particularly among mid- to later-life adults. However, its impact on early mortality (deaths occurring before reaching the oldest old age of 85 years) remains underexplored. This study examined the predictive role of loneliness on early mortality across different age groups using data from the Health and Retirement Study (HRS).
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