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Article Abstract
Recent findings reveal that macrophages actively control clearance by desialylating target cells via NEU1 and releasing cathepsin-cleaved calreticulin (CALR) to mark them for phagocytosis. This uncovers a dual role for CALR as immune activator or repressor, depending on its form and context, with distinct implications for cancer immunity.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12258218 | PMC |
| http://dx.doi.org/10.1080/2162402X.2025.2533494 | DOI Listing |
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