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The first Better evidence and RecommendatIons for the next Generation HealTh-BRIGHT symposium was held in Chongqing, China between June 21 and 23, 2024. The symposium did not only showcase the recent progress made by multidisciplinary teams in generating and translating evidence for children's healthcare, guideline development and evaluation, and the utilization of AI applications in pediatrics but also fostered transnational and transregional cooperation to promote the advancement of high-quality evidence and guidelines in this field. The symposium contributed significantly to the future development and transformation of research endeavors in pediatrics.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118297 | PMC |
http://dx.doi.org/10.1002/pdi3.2513 | DOI Listing |
Ann Intern Med
September 2025
Department of Medicine, Johns Hopkins University School of Medicine, and Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (J.B.S.).
Electronic health record (EHR) data are increasingly used to develop prediction models that guide clinical decision making at the point of care. These include algorithms that use high-frequency data, like in sepsis prediction, as well as simpler equations, such as the Pooled Cohort Equations for cardiovascular outcome prediction. Although EHR data used in prediction models are often highly granular and more current than other data, there is systematic and nonsystematic missingness in EHR data as there is with most data.
View Article and Find Full Text PDFFish Physiol Biochem
September 2025
Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKM's Narsee Monjee Institute of Management Studies, Mumbai, 56, India.
Zebrafish models have been used to research Alzheimer's disease and other neurodegenerative disorders because of their similarities to the human genetic composition and behavior. Researchers have detected iron accumulation in the post-mortem brain sections of neurodegenerative disorder patients. Therefore, the development an animal model to simulate these clinical pathological findings is important.
View Article and Find Full Text PDFJ Integr Neurosci
August 2025
CIBA Center for Advanced Biomedical Research, School of Medicine, Autonomous University of Queretaro, 76010 Querétaro, México.
Background: Neurofibrillary tangles, composed of hyperphosphorylated tau, have been implicated in the cognitive impairments observed in Alzheimer's disease. While the precise mechanism remains elusive, cognitive deficits in Alzheimer's disease have been associated with disrupted brain network activity. To investigate this mechanism, researchers have developed several tau transgenic models.
View Article and Find Full Text PDFF1000Res
September 2025
Departamento de Ciencias Administrativas, Instituto Tecnológico Metropolitano, Medellín, Colombia.
Background: The automation of processes and services has transformed various industries, including the restaurant sector. Technologies such as the Internet of Things (IoT), machine learning, Radio Frequency Identification (RFID), and big data have been increasingly adopted to enhance service delivery, improve user experiences, and enable data traceability. By collecting user feedback and analyzing sentiments, these technologies facilitate decision-making and offer predictive insights into future food preferences.
View Article and Find Full Text PDFJ Hosp Palliat Care
September 2025
Medical Social Work Team, Seoul National University Bundang Hospital, Seongnam, Korea.
Purpose: This study aimed to explore the job experiences of early-career social workers with <2 years of experience in hospice and palliative care, examine the expectations of related stakeholders, and propose policy recommendations for the advancement of this field.
Methods: Two focus group interviews were conducted with 10 early-career social workers working in hospice and palliative care settings, and the findings were analyzed using a constant comparative method.
Results: The analysis revealed that while early-career social workers experienced personal growth and a sense of fulfillment in their roles, they also faced various challenges as they adapted to the unique environment and intervention approaches of hospice and palliative care teams.