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Background: Our understanding of facial anatomy has expanded recently through the introduction of the concept of facial biomechanics. A pivotal aspect in the concept of facial biomechanics is the presence of facial ligaments, which, by anchoring the layered soft tissue envelope of the face, create zones of adhesion that are essential pillars of the biomechanics of the face. This study analyzes the force required to penetrate the major facial ligaments forming the line of ligaments.
Methods: Two fresh-frozen human cephalic cadavers were utilized and the force required to penetrate the facial ligaments (i.e., temporal ligamentous adhesion, lateral orbital thickening, zygomatic ligament proper, mandibular ligament) was measured using a 21-G cannula attached to a motorized force tester.
Results: The greatest force required to penetrate the ligament was measured for the zygomatic ligament proper with 9.16 ± 0.63 N [range 7.79-10.10 N], followed by the zygomatic retaining ligament with 8.01 ± 0.98 N [range 5.93-9.40 N]. The force required to penetrate the mandibular ligament was measured with 3.64 ± 0.81 N [range 2.20-4.65 N]. The force required to penetrate the temporal ligamentous adhesion and the lateral orbital thickening were measured with a mean of 3.16 ± 0.52 N [range 2.15-3.90 N] and 2.90 ± 0.31 N [range 2.36-3.40 N], respectively.
Conclusion: Understanding the different strengths of facial ligaments is essential for enhancing the effectiveness and safety of facial esthetic procedures, both surgical and non-surgical.
Level Of Evidence V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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http://dx.doi.org/10.1007/s00266-025-05060-y | DOI Listing |
Angew Chem Int Ed Engl
September 2025
Stoddart Institute of Molecular Science, Department of Chemistry, Zhejiang University, Hangzhou, 310058, P.R. China.
Mechanoresponsive molecular devices are capable of exhibiting dynamic responses to external mechanical stimuli, enabling applications in smart materials, nano-devices, and flexible electronics. However, energy conversion induced by mechanical stimuli requires efficient energy dissipation mechanisms. Traditional methods often involve bond breaking or incomplete energy release, which can lead to device failure during continuous operations.
View Article and Find Full Text PDFEur Radiol
September 2025
Department of Medical Physics, Isala Hospital, Zwolle, The Netherlands.
Objectives: Establishing paediatric DRLs is challenging due to sparse data availability. The objective was to assess paediatric fluoroscopic dose levels in Dutch clinical practice, as current diagnostic reference levels (DRLs) need updating following the European Guidelines on DRLs for Paediatric Imaging (PiDRL).
Material And Methods: Air Kerma-area Product (KAP) values were retrospectively collected from paediatric patients (0-18 years) who underwent fluoroscopic procedures in nine Dutch hospitals between 01-01-2017 and 01-06-2021.
Indian Heart J
September 2025
Department of Medicine, Fortis Hospital, Kangra, India.
Background: An inward force is experienced by the guide catheter during device retrieval resulting in potential risk of deep engagement into the ostio-proximal coronary segment. This undesired movement can result in coronary injury. There is no systematic data or reports of techniques to prevent such inadvertent guide movement during difficult retrieval of devices.
View Article and Find Full Text PDFAm J Pharm Educ
September 2025
Department of Pharmacotherapy, University of Utah College of Pharmacy, 30 South 2000 East, Salt Lake City, Utah 84112. Electronic address:
The accelerating adoption of artificial intelligence (AI), particularly large language models (LLMs) such as ChatGPT, has raised critical questions about the role of pharmacists and the potential for AI to substitute for human expertise in pharmaceutical care. Grounded in Porter's Five Forces framework-specifically the threat of substitutes-this commentary explores whether AI can adequately fulfill the complex and relational functions of pharmacists in delivering care to patients. Drawing from foundational definitions of pharmaceutical care and economic theories of substitution, the paper examines both historical and emerging competitors to pharmacist-provided services, including physicians, nurses, and now AI-powered tools.
View Article and Find Full Text PDFJ Mech Behav Biomed Mater
September 2025
Department of Biomechanical Engineering, Faculty of Engineering Technology, University of Twente, Enschede, 7522 NB, the Kingdom of the Netherlands. Electronic address:
In orthopaedic surgical procedures, bone cutting is often performed with an oscillating saw. Achieving an optimal cut requires high accuracy, low temperature, minimal surgeon effort, and time efficiency, all of which may be influenced by the forces applied on the sawing device, and the microstructure of the cut bone. The relation between bovine bone microstructure and sawing forces has been studied.
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