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Purpose: To determine the risk factors for complications after hip or knee replacement surgery in elderly patients.
Methods: In total, 401 elderly patients (aged ≥ 65 years) who underwent hip or knee replacement surgery at a hospital from January 2017 to December 2022 were retrospectively analyzed. Univariate analysis was performed to identify significant variables. Risk factors and the effects of the model were examined by unconditional binary logistic regression analyses and receiver operating characteristic (ROC) curve analysis, respectively.
Results: A total of 122 (30.42%) patients were diagnosed with complications after hip or knee replacement surgery, and the independent risk factors for complications were age, body mass index (BMI) and hypertension. Fifty-six patients (13.97%) developed lower extremity venous thrombosis (LEVT), and the independent risk factors were hypertension, surgical joint type and visual analog scale (VAS) pain score. Cardiopulmonary complications occurred in 50 patients (12.47%), and the independent risk factors were age and BMI. Postoperative delirium occurred in 15 patients (3.74%), and its independent risk factors were age and American Society of Anesthesiologists (ASA) grade. Two or more complications occurred in 17 patients (4.24%), and the independent risk factors were age and diabetes.
Conclusions: This study focused on elderly patients with risk factors for complications after hip or knee replacement surgery. Clinically, elderly patients undergoing hip or knee replacement surgery should perform well in terms of preoperative and perioperative management.
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http://dx.doi.org/10.1186/s12891-025-08742-5 | DOI Listing |
Clin Transl Oncol
September 2025
Spanish Society of Medical Oncology (SEOM) Thrombosis and Cancer Group, Madrid, Spain.
Purpose: To determine the real-world incidence and predictive factors for venous and arterial thromboembolic events (VTE/AT) in ovarian cancer patients treated with poly-(ADP-ribose) polymerase inhibitors (iPARP).
Methods/patients: A multicenter retrospective study involving 329 ovarian cancer patients who initiated iPARP treatment between January 2015 and December 2022. The primary outcome was the incidence of VTE/AT.
J Robot Surg
September 2025
Department of Urology, Rennes University Hospital, Rennes, France.
The surgical approach of ureteral stricture has changed dramatically over the past 15 years with the rise of robotic upper urinary tract reconstruction. This study aimed to evaluate the outcomes of all robotic ureteral reconstructions performed at a single academic center for ureteral stricture and to assess the predictive factors of stricture recurrence. The charts of all patients who underwent robot-assisted ureteral reconstruction between 2013 and 2024 at a single academic center were retrospectively reviewed.
View Article and Find Full Text PDFEnviron Geochem Health
September 2025
Policy Research Center for Environment and Economy, Ministry of Ecology and Environment of the People's Republic of China, Beijing, 100101, China.
The behavior of polycyclic aromatic hydrocarbons (PAHs) released from tire road wear particles (TRWPs) in human digestive fluids may pose a significant risk to human health. However, the current understanding of the release pattern and influencing factors of PAHs from TRWPs is still insufficient. In this study, the release characteristics of PAHs from UV-aging TRWPs (ATRWPs) were systematically investigated by in vitro digestive simulation experiments, release kinetic model fitting and control variable experiments.
View Article and Find Full Text PDFJ Clin Ultrasound
September 2025
Hebei General Hospital, Shijiazhuang, China.
Background: Acute ischemic stroke (AIS) is characterized by high incidence, sudden onset, and often poor prognosis. Carotid atherosclerosis plays a crucial role in its pathogenesis, and ultrasound imaging offers a non-invasive method for evaluating carotid plaque characteristics. This study aimed to develop and validate a prediction model for AIS risk based on a novel ultrasound-based carotid plaque scoring system combined with clinical risk factors.
View Article and Find Full Text PDFNpj Ment Health Res
September 2025
Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin (Campus Charité Mitte), Berlin, Germany.
Loneliness is a growing global health issue, yet real-time assessments of its objective risk and protective factors are limited. This study identifies momentary and daily predictors using digital phenotyping and temporal analysis. Analyzing 12788 momentary observations from social mobile sensing and actigraphy, we examined how they impact loneliness on average (between-person) and in daily fluctuations (within-person).
View Article and Find Full Text PDF