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As deep learning continues to advance in medical analysis, the increasing complexity of models, particularly Convolutional Neural Networks (CNNs), presents significant challenges related to interpretability, computational costs, and real-world applicability. These issues are critical in the medical domain, e.g., Attention Deficit Hyperactivity Disorder (ADHD) diagnosis, where model efficiency and interpretability are paramount. This paper proposes a novel parameter-efficient framework based on the Kolmogorov-Arnold Network (KAN) to overcome these challenges. Unlike CNNs, KAN restructures feature transformations, significantly reducing parameter overhead while preserving high classification accuracy. An attention-driven feature selection mechanism dynamically prioritizes the most significant features, minimizing irrelevant features and unnecessary computational load. Recognizing the complex and diverse nature of ADHD- related brain connectivity features, a novel activation function with learnable coefficients is introduced, enabling adaptive transformation based on specific data patterns. To further enhance model generalization, an advanced sliding window-based data augmentation technique is incorporated to meet substantial data requirements for training. Extensive experimentation on the benchmark ADHD-200 dataset demonstrates the model's superiority, achieving an accuracy of 79.25 %, an F1-score of 78. 75 % and a precision of 78.23 %, surpassing many state-of-the-art ADHD studies. Remarkably, these results are achieved using only a few thousand parameters compared to the millions required by many existing approaches, making it valuable for various resource-constrained researchers and organizations. The proposed framework, seamlessly fusing KAN, attention-driven feature selection, adaptive activation, and robust data augmentation, achieves substantial parameter reduction with enhanced performance. This lightweight architecture, combined with superior performance and interpretability, makes the proposed model highly promising for ADHD diagnosis and other complex medical applications.
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http://dx.doi.org/10.1016/j.pscychresns.2025.112016 | DOI Listing |
Arch Clin Neuropsychol
September 2025
School of Psychology, Western Sydney University, Sydney, Australia.
Objective: Although traditionally associated with mild head trauma, post-concussive symptoms are commonly reported across both healthy and other clinical populations. Existing research indicates that individuals with depression report high levels of post-concussive symptoms, though the underlying causes of this association remain unknown. The current study aimed to explore potential factors underlying this relationship: specifically, how maladaptive and adaptive self-focused cognitive coping styles, namely, rumination and reflection, respectively, differentially contribute to post-concussive symptoms.
View Article and Find Full Text PDFFront Child Adolesc Psychiatry
August 2025
Faculty of Medicine, Veracruzana University, Minatitlan, Mexico.
Parents of children with autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) face unique challenges that may significantly increase stress levels, potentially impacting the emotional well-being of the entire family. In Mexico, limited research has examined the association between parental stress and coping strategies among families with children with developmental disabilities. This study aimed to compare stress levels and coping strategies among parents of children with ASD, ADHD, and neurotypical developing (NTD) children, as well as to analyze differences in coping styles across these groups.
View Article and Find Full Text PDFNeuroimage Rep
September 2025
Arizona State University, Tempe, AZ, 85287, USA.
Non-intrusive neuroimaging technology offers fast and robust diagnostic tools for neuro-disorder disease diagnosis, such as Attention-Deficit/Hyperactivity Disorder (ADHD). Resting-state functional magnetic imaging (rs-fMRI) has been demonstrated to have great potential for such applications due to its unique capability and convenience in providing spatial-temporal brain imaging. One critical challenge of using rs-fMRI data is the high dimensionality for both spatial and temporal domains.
View Article and Find Full Text PDFFront Neurol
August 2025
Unit of Child Neurology and Psychiatry, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy.
Introduction: Restless Legs Syndrome (RLS), known as Willis-Ekbom disease, is a common neurological condition that often goes undiagnosed, especially in children. Characterized by an irresistible urge to move the legs, it is typically more pronounced in the evening and at rest. Growing Pains (GP), common in childhood and associated with migraine, present apparently overlapping symptoms with RLS, making it sometimes difficult to distinguish between the two.
View Article and Find Full Text PDFBrain Behav
September 2025
Child Development Department, Faculty of Health Sciences, Hacettepe University, Ankara, Turkey.
Purpose: The study aims to assess familial and environmental characteristics and daily routines (nutrition, sleep, and screen time) associated with attention-deficit/hyperactivity disorder (ADHD) in Turkish children and compare them with typically developing peers.
Methods: A case-control study was conducted with 106 ADHD-diagnosed children and 100 typically developing peers. Data were analyzed using descriptive statistics and logistic regression models to determine risk factors for ADHD.