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Precision agriculture harnesses data-driven techniques to optimize crop production, resource use, and sustainability. However, low-income countries like Bangladesh face a shortage of localized, high-quality datasets that reflect regional agroclimatic conditions and cropping practices. To address this gap, we present SPAS-Dataset-BD, a robust dataset compiled through a hybrid approach: secondary extraction from the Bangladesh Bureau of Statistics (BBS) 2022 Yearbook and primary on-field surveys of 223 farmers across ten diverse districts. The dataset comprises 4191 records over 73 crop types, with 12 agronomic and environmental features, including underrepresented species. Robustness is demonstrated via threshold-based missing-value handling (<5 % deletion, targeted imputation), hash-based deduplication, and cross-validation against official statistics. We illustrate potential applications, in machine learning (73-class crop classification, yield forecasting) and IoT-driven irrigation scheduling. SPAS-Dataset-BD's scale, methodological transparency, and contextual richness make it a valuable resource for precision agriculture research and policy-making in South Asia.
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http://dx.doi.org/10.1016/j.dib.2025.111727 | DOI Listing |
Biotechnol J
September 2025
Department of Molecular Biosciences and Bioengineering, University of Hawai'i at Mānoa, Honolulu, Hawai'i, USA.
CRISPR technologies are rapidly transforming agriculture by enabling precise and programmable modifications across a wide range of organisms. This review provides an overview of CRISPR applications in crops, livestock, aquaculture, and microbial systems, highlighting key advances in sustainable agriculture. In crops, CRISPR has accelerated the improvement of traits such as drought tolerance, nutrient efficiency, and pathogen resistance.
View Article and Find Full Text PDFGenome Biol
September 2025
National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan, 430070, China.
Background: Soil salinization represents a critical global challenge to agricultural productivity, profoundly impacting crop yields and threatening food security. Plant salt-responsive is complex and dynamic, making it challenging to fully elucidate salt tolerance mechanism and leading to gaps in our understanding of how plants adapt to and mitigate salt stress.
Results: Here, we conduct high-resolution time-series transcriptomic and metabolomic profiling of the extremely salt-tolerant maize inbred line, HLZY, and the salt-sensitive elite line, JI853.
Trends Biotechnol
September 2025
Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, 9747 AG, The Netherlands; Department of Bioengineering, Imperial College London, South Kensington Campus, London, SW72AZ, UK; Bezos Centre for Sustainable Protein, Imperial Colleg
The breach of six planetary boundaries highlights the need for sustainable food production. Aerobic hydrogen-oxidising bacteria (HOBs) convert atmospheric CO and green hydrogen (H) into biomass via gas fermentation, a process already used for food-grade single-cell protein production. This approach enables a supply chain independent of agriculture, requiring minimal land and water, with potential for carbon-neutral production and carbon capture.
View Article and Find Full Text PDFBiotechnol Adv
September 2025
College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China; National Engineering Research Center for Fruit and Vegetable Processing, Beijing, China; Key Laboratory of Fruit and Vegetable Processing, Ministry of Agriculture and Rural Affairs, Beijing, Ch
Precision fermentation represents an innovative cell-based production approach that employs synthetic biology and metabolic engineering tools, revolutionizing global food production by utilizing "microbial cell factories" to produce added-value ingredients. However, its global implementation is hindered by technological and scalability bottlenecks, regulatory fragmentation, regional accessibility and consumer acceptance, and nutritional trade-offs challenges. This review utilizes illustrated case studies and modeling analysis to present a detailed exploration of precision fermentation intersecting with global cell-based food production, discussing actionable research gaps and insights as well as advanced bioengineering practices and analytical techniques, to address these challenges for ongoing academic research, industrial applications and policy initiatives, thus supporting the transition of fermentation-enabled food production toward efficient and sustainable manufacturing.
View Article and Find Full Text PDFMed Oncol
September 2025
Department of Biotechnology, Institute of Engineering and Management, University of Engineering and Management, Kolkata, Kolkata, India.
Oligomeric proanthocyanidins (OPCs), condensed tannins found plentiful in grape seeds and berries, have higher bioavailability and therapeutic benefits due to their low degree of polymerization. Recent evidence places OPCs as effective modulators of cancer stem cell (CSC) plasticity and tumor growth. Mechanistically, OPCs orchestrate multi-pathway inhibition by destabilizing Wnt/β-catenin, Notch, PI3K/Akt/mTOR, JAK/STAT3, and Hedgehog pathways, triggering β-catenin degradation, silencing stemness regulators (OCT4, NANOG, SOX2), and stimulating tumor-suppressive microRNAs (miR-200, miR-34a).
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