98%
921
2 minutes
20
Purpose: Acceleration-speed (AS) profiling provides a novel way to quantify soccer players' maximum running ability without requiring dedicated sprint tests. This study explored how normalizing player effort with AS profiles could reveal unique patterns of changes in effort compared with nonnormalized absolute values during distinct goal differential conditions throughout matches and across positions.
Methods: AS profiles were developed from global navigation satellite system sensor data from 3 years of match play from a women's national soccer team. Acceleration and power data were then grouped into low, moderate, high, and very high speed domains using either nonnormalized maximum values or normalized values based on individualized AS profiles. Separate linear mixed model analyses were carried out for normalized and nonnormalized data.
Results: The analysis revealed that when examining changes in acceleration effort based on goal differential, both normalized and nonnormalized values showed a general increase in effort when either in a draw, or winning in the first half, and a general trend in sustained effort when losing in the first half or losing/drawn throughout the match. Furthermore, differences were mostly displayed at high to very high running-speed domains for normalized and moderate- to low-speed zones for nonnormalized metrics.
Conclusions: These findings highlight the value of using individual AS and power profiles to normalize effort to facilitate investigation of player- and position-specific differences and reveal important positional behaviors displayed when in draw, losing, or winning states from first to second halves.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1123/ijspp.2025-0017 | DOI Listing |
Front Endocrinol (Lausanne)
September 2025
Guangxi Key Laboratory of Tumor Immunology and Microenvironmental Regulation, Guilin Medical University, Guilin, China.
Endometrial cancer (EC) is one of the most common gynecological cancers in developed countries. Like EC, most female reproductive tract malignancies are thought to be hormonally driven, with estrogen signaling acting as an oncogenic signal. The actions of estrogen are mediated through the classical nuclear estrogen receptors α (ER-α) and β (ER-β) as well as transmembrane G protein-coupled estrogen receptors (GPR30 and GPER).
View Article and Find Full Text PDFBlood Cells Mol Dis
September 2025
NHC Key Laboratory of Thalassemia Medicine, The First Afliated Hospital of Guangxi Medical University, Nanning, Guangxi, China; Guangxi Key Laboratory of Thalassemia Research, Life Sciences Institute, Guangxi Medical University, Nanning, Guangxi, China. Electronic address:
Objective: In patients with severe β-thalassemia, fetal hemoglobin (HbF) upregulation may provide an avenue to better therapeutic outcomes. The mechanisms that regulate the expression of HbF, however, are currently unclear. This study was developed with the goal of exploring biomarkers and molecular mechanisms associated with HbF expression to help inform the development of novel therapeutic strategies.
View Article and Find Full Text PDFNat Aging
September 2025
Aging Biomarker Consortium (ABC), Beijing, China.
The global surge in the population of people 60 years and older, including that in China, challenges healthcare systems with rising age-related diseases. To address this demographic change, the Aging Biomarker Consortium (ABC) has launched the X-Age Project to develop a comprehensive aging evaluation system tailored to the Chinese population. Our goal is to identify robust biomarkers and construct composite aging clocks that capture biological age, defined as an individual's physiological and molecular state, across diverse Chinese cohorts.
View Article and Find Full Text PDFDev Cell
September 2025
Department of Pharmacology, University of Cambridge, Cambridge, UK; Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. Electronic address:
Single-cell studies on breast tissue have contributed to a change in our understanding of breast epithelial diversity that has, in turn, precipitated a lack of consensus on breast cell types. The confusion surrounding this issue highlights a possible challenge for advancing breast atlas efforts. In this perspective, we present our consensus on the identities, properties, and naming conventions for breast epithelial cell types and propose goals for future atlas endeavors.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
September 2025
Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202.
Retinal ganglion cells (RGCs) are highly compartmentalized neurons whose long axons serve as the sole connection between the eye and the brain. In both injury and disease, RGC degeneration occurs in a similarly compartmentalized manner, with distinct molecular and cellular responses in the axonal and somatodendritic regions. The goal of this study was to establish a microfluidic-based platform to investigate RGC compartmentalization in both health and disease states.
View Article and Find Full Text PDF