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Identifying influential nodes in complex networks is essential for a wide range of applications, from social network analysis to enhancing infrastructure resilience. While quantum walk-based methods offer potential advantages, existing approaches face challenges in dimensionality, computational efficiency, and accuracy. To address these limitations, this study proposes a novel method inspired by the one-dimensional discrete-time quantum walk (IOQW). This design enables the development of a simplified shift operator that leverages both self-loops and the network's structural connectivity. Furthermore, degree centrality and path-based features are integrated into the coin operator, enhancing the accuracy and scalability of the IOQW framework. Comparative evaluations against state-of-the-art quantum and classical methods demonstrate that IOQW excels in capturing both local and global topological properties while maintaining a low computational complexity of O(N⟨k⟩), where ⟨k⟩ denotes the average degree. These advancements establish IOQW as a powerful and practical tool for influential node identification in complex networks, bridging quantum-inspired techniques with real-world network science applications.
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http://dx.doi.org/10.3390/e27060634 | DOI Listing |
BMC Pulm Med
September 2025
Division of Cellular Pneumology, Priority Area Infections, Research Center Borstel, Leibniz Lung Center, Borstel, 23845, Germany.
Background: Volatile anesthetics are gaining recognition for their benefits in long-term sedation of mechanically ventilated patients with bacterial pneumonia and acute respiratory distress syndrome. In addition to their sedative role, they also exhibit anti-bacterial and anti-inflammatory properties, though the mechanisms behind these effects remain only partially understood. In vitro studies examining the prolonged impact of volatile anesthetics on bacterial growth, inflammatory cytokine response, and surfactant proteins - key to maintaining lung homeostasis - are still lacking.
View Article and Find Full Text PDFNat Biomed Eng
September 2025
Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Phenotype-driven approaches identify disease-counteracting compounds by analysing the phenotypic signatures that distinguish diseased from healthy states. Here we introduce PDGrapher, a causally inspired graph neural network model that predicts combinatorial perturbagens (sets of therapeutic targets) capable of reversing disease phenotypes. Unlike methods that learn how perturbations alter phenotypes, PDGrapher solves the inverse problem and predicts the perturbagens needed to achieve a desired response by embedding disease cell states into networks, learning a latent representation of these states, and identifying optimal combinatorial perturbations.
View Article and Find Full Text PDFVet Anaesth Analg
July 2025
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Objective: To determine the use of Air-Test in ventilated, anaesthetized dogs for evaluating oxygen uptake and to determine its potential utility in guiding the decision to perform an alveolar recruitment manoeuvre (ARM).
Study Design: Retrospective cohort study.
Animals: A total of 25 client-owned dogs undergoing general anaesthesia.
Anesth Prog
September 2025
Objective: The purpose of this study was to compare nitrous oxide (N2O) vs virtual reality (VR) as methods for reducing pain and anxiety during a dental injection. The primary objectives were to assess acute changes in stress responses by comparing salivary cortisol levels between the 2 groups and differences in injection pain scores.
Methods: A total of 132 female subjects serving as their own control received maxillary lateral incisor infiltration injections with the use of either N2O or a VR headset during separate appointments spaced at least 2 weeks apart.
Bioinspir Biomim
September 2025
Mechanical Intelligence (MI) Research Group, London South Bank University, 103 Borough Road, London, London, SE1 0AA, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.
Conventional rigid grippers remain the most-used robotic grippers in industrial assembly tasks. However, they are limited in their ability to handle a diverse range of objects. This study draws inspiration from nature to address these limitations, employing multidisciplinary methods, such as computer-aided design, parametric modeling, finite element analysis, 3D printing, and mechanical testing.
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