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Fish maw (FM), the dried swim bladders of fish, is highly valued for its nutritional and pharmacological properties due to its high collagen content, a source of fish gelatin. In traditional Chinese medicine, FM is typically processed with clamshell powder (CP), called CP-FM. This study evaluated the effects of stir-frying FM with CP on its physicochemical properties. These results revealed that CP-FM significantly enhanced physicochemical properties compared to FM. Fourier-transform infrared spectroscopy indicated strong interactions between collagen and calcium ions (Ca), and electron microscopy confirmed the presence of peptide‑calcium chelates in CP-FM. Additionally, integrative omics analysis uncovered alterations in the abundance of collagen and modifications in N-glycosylation sites, particularly in type I collagen. These modifications enhanced the Ca binding capability of the collagen, thereby improving the stability and overall quality of FM gelatin. This research highlights the positive impact of CP as an ingredient during the stir-frying process and provides valuable insights into the implications of processing dried seafood.
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http://dx.doi.org/10.1016/j.foodchem.2025.145196 | DOI Listing |
J Sci Food Agric
September 2025
Department of Nutrition and Dietetics, Hamidiye Faculty of Health Sciences, University of Health Sciences, Istanbul, Türkiye.
Background: This study aimed to develop gluten-free bread from chickpea flour by incorporation of varying levels (0 (B-C), 2.5 (B-1), 5 (B-2), and 10 g kg (B-3)) of madımak leaf powder (MLP), and to investigate its effect on physicochemical and bioactive properties, glycemic index, texture, and sensory attributes.
Results: Moisture ranged from 229 (B-3) to 244 g kg (control), while ash content increased with MLP, reaching 47 g kg in B-3 compared to 15.
Mater Today Bio
October 2025
School of Pharmacy, Henan Medical University, Xinxiang, Henan, China.
Breast cancer continues to present a major clinical hurdle, largely attributable to its aggressive metastatic behavior and the suboptimal efficacy of standard chemotherapeutic regimens. Cisplatin (CDDP) is a representative platinum drug in the treatment of breast cancer, however, its therapeutic application is often constrained by systemic toxicity and the frequent onset of chemoresistance. Here, we introduce a novel charge-adaptive nanoprodrug system, referred to as PP@, engineered to respond to tumor-specific conditions.
View Article and Find Full Text PDFFood Chem X
August 2025
Department of Toxicology, İstanbul Aydın University, P.O. Box 65, 00014 Istanbul, Turkey.
This study investigated the effect of refining time on the physicochemical and functional properties of anhydrous cream prepared from a palm-sunflower oil blend using a stirred ball mill. Refining was performed for 0-300 min, and its impact on particle size distribution, rheology, oxidative stability, and thermal behavior was assessed. The target particle fineness (D90 ≤ 30 μm) was achieved at approximately 180 min, with negligible reduction thereafter.
View Article and Find Full Text PDFRSC Adv
September 2025
Process and Environmental Engineering Laboratory (LIPE), Faculty of Chemistry, University of Science and Technology of Oran Mohamed Boudiaf P. O. Box 1503, El Mnaouer 31000 Oran Algeria.
In this contribution, Molecular Electron Density Theory (MEDT) is employed to investigate the (3 + 2) cycloaddition reaction between ()--methyl--(2-furyl)-nitrone 1 and but-2-ynedioic acid 2. DFT calculations at the M06-2X-D3/6-311+G(d,p) level of theory under solvent-free conditions at room temperature show that this reaction proceeds CA3-Z diastereoselectivity, with the formation of the CA3-Z cycloadduct being both thermodynamically and kinetically more favoured than the CA4-Z one. Reactivity parameters obtained from CDFT calculations reveal that compound 1 predominantly behaves as a nucleophile with moderate electrophilic features, in contrast to compound 2, which demonstrates strong electrophilicity and limited nucleophilic ability.
View Article and Find Full Text PDFVet World
July 2025
Akkhraratchakumari Veterinary College, Walailak University, Nakhon Si Thammarat, 80160, Thailand.
Background And Aim: Probiotic viability remains a critical challenge during gastrointestinal (GI) transit, storage, and feed processing. Conventional encapsulation materials often fail under acidic and thermal stress. This study aimed to develop and characterize a novel, eco-friendly microencapsulation system using (FP) seed extract as a natural encapsulating matrix for (LP) WU2502, enhancing its functional resilience and storage stability.
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