Bactericidal Activities of Nanoemulsion Containing L. Leaf and Hydroxychavicol Against Avian Pathogenic and Modelling Simulation of Hydroxychavicol Against Bacterial Cell Division Proteins.

: Avian pathogenic (APEC) is a leading cause of colibacillosis in poultry. L. is a medicinal plant rich in bioactive compounds including hydroxychavicol that possess potent antibacterial activity.

Whole Genome Sequence Analysis of Multidrug-Resistant and Isolated from Superficial Pyoderma in Dogs and Cats.

: Pyoderma is a superficial bacterial infection that is considered the formation of pus-containing lesions on the skin occurring in animals. Staphylococci, including and , that cause pyoderma in pet animals is a global health concern. The objectives of this study were to investigate antibiotic-resistant staphylococci isolated from pyoderma in dogs and cats and to analyse whole genome sequences of multidrug-resistant (MDR) staphylococci.

and investigations of Propolis-derived phytochemicals as potential inhibitors of .

Background And Aim: Malaria continues to pose a global health challenge, exacerbated by the emergence of drug-resistant strains of . This study aimed to evaluate the anti- potential of Propolis extracts collected from various Iranian regions and to characterize the molecular interactions of their bioactive phytochemicals with lactate dehydrogenase (PfLDH), a key enzyme in parasite glycolysis.

Materials And Methods: The anti- activity of ethanol-extracted Propolis was assessed against NF54 using the SYBR Green I fluorescence assay.

Extended-Spectrum β-lactamase-Producing in Retail Pork and Market Environments: Genetic Diversity and Antimicrobial Resistance in Thailand.

The increasing prevalence of extended-spectrum β-lactamase (ESBL)-producing () highlights the growing issue of multidrug resistance within the food processing chain. This study aimed to determine the prevalence, antimicrobial resistance profiles, molecular genetic structures, and genetic diversity of ESBL-producing isolated from pork, cutting boards, and knives. A total of 90 samples were collected from 10 local markets in Southern Thailand.

Effects of heat stress on egg performance in laying hens under hot and humid conditions.

Background And Aim: Egg production is a critical indicator of reproductive efficiency in laying hens. High environmental temperatures and humidity expose laying hens to heat stress, adversely affecting egg production, egg quality, feed intake, blood chemistry, health, and behavior. Despite the global economic significance of egg production, research on the impact of heat stress in tropical climates, particularly in locally adapted breeds, remains limited.

Inhibition of quorum sensing regulation and stress tolerance by extracts and rhodomyrtone as an alternative treatment for zoonotic pathogens.

Background And Aim: is a zoonotic pathogen with significant public health and economic implications. Its ability to tolerate environmental stress and regulate virulence through quorum sensing contributes to its persistence and pathogenicity. and its bioactive compound rhodomyrtone have demonstrated antimicrobial properties against Gram-positive, multidrug-resistant bacteria.

Multidrug Resistance, Biofilm-Forming Ability, and Molecular Characterization of Species Isolated from Foods in Thailand.

Background: species are common foodborne pathogens that cause gastrointestinal tract inflammation. Multidrug resistance (MDR) in spp. is a global health concern, especially in aquaculture systems and food chain systems.

Development of a novel encystment medium: Enhancing diagnostic potential of spp.

Background And Aim: spp. are pathogenic microorganisms linked to severe infections in humans and animals, requiring a deeper understanding of their encystation process for effective diagnostics and research. This study focused on developing a novel encystment medium to induce synchronized encystation of spp.

Amebicidal and Antiadhesion Activities of Extract Against T4 Genotype on Contact Lenses and Modeling Simulation of Its Main Compound, E2N, Against Beta-Tubulin.

Medicinal plants have been used as alternative agents for the treatment of infections. This study aimed to investigate bioactivities of medicinal plant extracts including extract (Kre) against T4 and . Anti- activities of 44 extracts from 5 plant species were determined.

Anti-adherent effects of bark and leaf extracts and computational prediction of the effects of its compound on β-tubulin interaction in genotype 4.

Background And Aim: , an opportunistic protozoan, exists widely in natural sources and can cause infections in humans and animals. The absence of effective monotherapy after the initial infection leads to chronic disease and recurrence. Tubulin protein is a vital target for design-targeted drug discovery.

Bactericidal and antibiofilm activities of extract against : and approaches.

biofilm is a significant virulence factor in infection. This study aimed to investigate antibacterial and antibiofilm activities of extract against . The MIC and MBC values of the extract against the isolates were 0.

spp. as Reservoirs of Multidrug Resistance- and Biofilm-Forming in Urban Community from Southern Thailand.

Rats are rodents commonly found in Thailand that carry various zoonotic pathogens. Bacterial zoonosis can occur in a shared environment between humans and rats, especially in human communities and agricultural areas. , particularly pathogenic and multidrug-resistant strains, is a significant public health concern that is transmitted by rats.

Comparative efficacy of extract delivery PEG--PCL, niosome, and their combination against genotype T4: characterization, inhibition, anti-adhesion, and cytotoxic activity.

Background: spp. is a waterborne, opportunistic protozoan that can cause amebic keratitis and granulomatous amebic encephalitis. is a native tree in Malaysia, and its extracts possess a broad range of biological activities.

Occurrence of multidrug-resistant in upper Southern Thailand.

Background And Aim: causes global concern with tuberculosis (TB). Multidrug-resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB) pose additional challenges, as they resist to multiple first-line drugs. This study investigated the occurrence of TB, antibiotic resistance due to and gene mutations, and multidrug resistance in during fiscal years 2020-2022.

Antibacterial, Antibiofilm, and Antioxidant Activities of Aqueous Crude Leaf Extract against Vancomycin-Resistant .

Vancomycin-resistant (VREF) causes nosocomial infections with high mortality and morbidity rates. This study aimed to evaluate the antibacterial and antibiofilm activities of aqueous crude leaf extract (GIE) against the VREF ATCC 700221 strain. The antimicrobial activity of GIE against VREF was performed using disk diffusion and broth microdilution.

Antibacterial and antibiofilm efficacy of Solanum lasiocarpum root extract synthesized silver/silver chloride nanoparticles against Staphylococcus haemolyticus associated with bovine mastitis.

Staphylococcus haemolyticus is a cause of bovine mastitis, leading to inflammation in the mammary gland. This bacterial infection adversely affects animal health, reducing milk quality and yield. Its emergence has been widely reported, representing a significant economic loss for dairy farms.

Inhibitory and anti-adherent effects of L. leaf extract against in co-infection with and : A sustainable one-health approach.

Background And Aim: Keratitis is a serious ocular infection often caused by pathogenic microorganisms such as spp. Among other harmful microbes, keratitis presents a particular challenge due to its resistance to conventional antimicrobial agents. Linn.

Antibiograms, multidrug resistance, and milk-related parameters of bacteria isolated from milk of dairy cattle in Phatthalung, Thailand.

Background And Aim: Milk, a nutritious food, is widely consumed in human diets; however, contamination by micro-organisms can negatively impact its quality and consumer health. Contamination by micro-organisms affects the quality of milk, which can affect the quality of the milk production chain. This study aimed to determine the changes in milk composition and antibiotic susceptibility related to bacteria isolated from dairy cow milk.

The infection of Cysticercus fasciolaris in natural rats (Rattus species) residing in human residence areas, Nakhon Si Thammarat, Thailand.

Cysticercus fasciolaris (C. fasciolaris) is the larval stage of a cestode parasite named Taenia taeniaeformis (T. taeniaeformis).

Preparation and evaluation of a niosomal delivery system containing extract and study of its anti- activity.

extract (GME) has severe pharmacokinetic deficiencies and is made up of a variety of bioactive components. GME has proven its anti- effectiveness. In this investigation, a GME-loaded niosome was developed to increase its potential therapeutic efficacy.

Antibacterial and antivirulence factor activities of protein hydrolysates from Phatthalung Sangyod rice ( L.) seeds against zoonotic and foodborne pathogens.

Background And Aim: Antimicrobial resistance is an emerging public health threat. Foodborne illnesses are typically caused by bacteria, such as , , , and , which are frequently resistant to common antimicrobial agents. Rice is a staple grain in most parts of the world.

extract and its application in bovine teat dipping solution inhibit and eliminate biofilms in bovine mastitis-inducing staphylococci.

Background And Aim: Staphylococci, including , , and , are significant bacteria that induce bovine mastitis, primarily because they can form biofilms in bovine teat canals. This study aimed to investigate the efficacy of extract and a bovine teat dipping solution containing extract (BSP) against these mastitis-causing staphylococci.

Materials And Methods: BSP was prepared using extract as the bioactive compound.

Acinetobacter baumannii in suspected bacterial infections: Association between multidrug resistance, virulence genes, & biofilm production.

Background Objectives: Acinetobacter baumannii has emerged as a nosocomial pathogen with a tendency of high antibiotic resistance and biofilm production. This study aimed to determine the occurrence of A. baumannii from different clinical specimens of suspected bacterial infections and furthermore to see the association of biofilm production with multidrug resistance and expression of virulence factor genes in A.

Occurrence of multidrug resistance associated with extended-spectrum β‑lactamase and the biofilm forming ability of Escherichia coli in environmental swine husbandry.

Extended-spectrum beta-lactamase (ESBL) production and biofilm formation are mechanisms employed by Escherichia coli to resist beta-lactam antibiotics. Thus, we aimed to examine antibiotic resistance associated with ESBL production and biofilm formation in E. coli isolates from swine farms in Southern Thailand.

Virulence factors and quorum sensing as targets of new therapeutic options by plant-derived compounds against bacterial infections caused by human and animal pathogens.

The emergence of antibiotic-resistant bacteria and hospital-acquired bacterial infection has become rampant due to antibiotic overuse. Virulence factors are secondary to bacterial growth and are important in their pathogenesis, and therefore, new antimicrobial therapies to inhibit bacterial virulence factors are becoming important strategies against antibiotic resistance. Here, we focus on anti-virulence factors that act through anti-quorum sensing and the subsequent clearance of bacteria by antimicrobial compounds, especially active herbal extracts.