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Metal-based nanoparticles (MNPs) are widely used in many aspects of production and life, resulting in their detection in various types of aquatic environments globally with mass concentrations mostly in the range of ng/L-μg/L. Therefore, more attention should be paid to considering realistic situations and exposure scenarios at environmentally relevant MNPs concentrations. With the support of new technology and methods, the environmental concentration distribution of MNPs in the aquatic environment was investigated and sorted out. In addition, based on environmentally relevant concentrations, the toxic effects of MNPs on aquatic organisms were systematically evaluated, including chronic toxicity, food chain transfer, and ecosystem impacts. Finally, the application of dynamic models to describe the behavior of nanoparticles in the components of aquatic ecosystems is discussed. Based on the above, future studies should conduct toxicological experiments based on environmental background data and integrate the parameters obtained from the experiments to construct more general predictive models, in order to achieve experimental-modelling synergistic means to provide more understanding and reference for the aquatic ecological risk of MNPs.
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http://dx.doi.org/10.1016/j.aquatox.2025.107454 | DOI Listing |
Int J Pharm
September 2025
Department of Chemistry, Adithya Institute of Technology, Coimbatore 641107 Tamil Nadu, India.
Chronic wounds are a foremost cause of death, affecting 6.5 million people annually. Traditional treatments, such as metal-based formulations and biomaterials, are ineffective due to their toxicity and the rising incidence of chronic wound cases, necessitating the advancement of new therapies for efficient wound healing.
View Article and Find Full Text PDFRSC Adv
August 2025
University of Technology Owerri, P.M.B 1526 Owerri Imo State Nigeria.
The global rise of antimicrobial resistance has intensified the search for novel therapeutic agents that act through non-conventional mechanisms. Gallium-based nanoparticles (GaNPs) represent a promising yet underexplored class of metal-based antimicrobials. Owing to their unique ability to mimic iron(iii), GaNPs disrupt key bacterial metabolic processes, particularly those dependent on iron acquisition and utilization.
View Article and Find Full Text PDFGeorgian Med News
June 2025
Department of Pharmacy, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan.
The study evaluated the inhibitory effects of pharmaceutical formulations enriched with metal-based nanoparticles on Staphylococcus aureus, Escherichia coli, and Salmonella dublin. Transmission electron microscopy revealed agglomerated chain-like structures of nanoparticles measuring 36-122 nm. Most metal components, including cobalt, zinc, manganese, and germanium, significantly reduced bacterial viability, whereas magnesium showed no suppressive effect.
View Article and Find Full Text PDFBiosensors (Basel)
August 2025
Department of Electrical and Electronics Engineering, Faculty of Engineering, Izmir Demokrasi University, 35140 Izmir, Türkiye.
Paper-based colorimetric biosensors represent a promising class of low-cost diagnostic tools that do not require external instrumentation. However, their broader applicability is limited by the environmental concerns associated with conventional metal-based nanomaterials and the subjectivity of visual interpretation. To address these challenges, this study introduces a proof-of-concept platform-using CA19-9 as a model biomarker-that integrates naturally derived melanin nanoparticles (MNPs) with machine learning-based image analysis to enable environmentally sustainable and analytically robust colorimetric quantification.
View Article and Find Full Text PDFZ Naturforsch C J Biosci
August 2025
Department of Food Technology, School of Agriculture, Maya Devi University, Dehradun, 248011, Uttarakhand, India.
In recent years, agriculture has undergone transformative innovations to enhance crop productivity, resilience, and nutritional value. With increasing concerns over food security, environmental degradation, and soil health, there is growing emphasis on sustainable agricultural practices. Among these strategies, the use of plant growth-promoting rhizobacteria (PGPR) have emerged as promising solutions.
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