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Background: In recent years, the rapid development of artificial intelligence (AI) in hepatobiliary surgery research has led to an increase in articles exploring its benefits. We performed a bibliometric analysis of AI applications in hepatobiliary surgery to better delineate the contemporary state of AI application in hepatobiliary surgery and potential future trajectories.
Aim: To provide clinical practitioners with a reliable reference point. It offers a detailed overview of the development of AI in hepatobiliary surgery by systematically examining the contributions of authors, countries, institutions, journals, and keywords in this domain over the last 10 years.
Methods: The academic resources utilized in this study were obtained from the Web of Science Core Collection database. The search results were subsequently integrated and imported into CiteSpace and VOSviewer software for the purpose of visual analysis.
Results: The study analyzed 2552 publications during 2014-2024. These publications collectively garnered 32 628 citations, averaging 15.66 citations per paper. The top contributor to this field was China. The USA had the highest citation count. The author with the highest citation count was Summers RM. In terms of the number of articles published, the leading journals were . Excluding the subject search terms, the most frequently used keywords included "classification", "CT and "diagnosis".
Conclusion: This bibliometric analysis indicates that research on AI in hepatobiliary surgery has entered a period of rapid development, particularly in the domain of disease imaging diagnostics.
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http://dx.doi.org/10.4240/wjgs.v17.i5.104728 | DOI Listing |
Nature
September 2025
Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Key Laboratory of RNA Innovation Science and Engineering, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Antigen-induced clustering of cell surface receptors, including T cell receptors and Fc receptors, represents a widespread mechanism in cell signalling activation. However, most naturally occurring antigens, such as tumour-associated antigens, stimulate limited receptor clustering and on-target responses owing to insufficient density. Here we repurpose proximity labelling, a method used to biotinylate and identify spatially proximal proteins, to amplify designed probes as synthetic antigen clusters on the cell surface.
View Article and Find Full Text PDFOncogene
September 2025
Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Pancreatic cancer is a highly aggressive malignancy with a dismal prognosis, characterized by a complex tumor microenvironment that promotes immunosuppression and limits the efficacy of immune checkpoint blockade (ICB) therapy. Fibroblast activation protein (FAP) is overexpressed in the tumor stroma and represents a promising target for therapeutic intervention. Here, we developed a novel antibody-drug conjugate (ADC) targeting FAP, and investigated its anti-tumor activity and ability to enhance ICB efficacy in pancreatic cancer.
View Article and Find Full Text PDFJ Int Med Res
September 2025
Department of Hepatobiliary Surgery, The Affiliated People's Hospital of Ningbo University, China.
This study explores effective treatment methods for chronic secondary lymphedema after radical cervical cancer surgery combined with pelvic lymphadenectomy. In cases where conservative treatment was ineffective, we investigated whether multiple injections of indocyanine green can effectively improve the outcomes of lymphatic-venous anastomosis under microscopy. Preoperative lymphatic imaging was used to localize functional vessels, guiding distal left lower limb lymphatic reconstruction.
View Article and Find Full Text PDFComput Med Imaging Graph
August 2025
Academy for Engineering and Technology, Fudan University, Shanghai, 200433, People's Republic of China; Department of Radiology, Huashan Hospital, Fudan University, Shanghai, 200040, People's Republic of China; Shanghai Engineering Research Center of Intelligent Imaging for Critical Brain Diseases,
Recent advancements in artificial intelligence have significantly enhanced the efficiency of abdominal MRI segmentation, thereby improving the screening and diagnosis of liver diseases. However, accurate precise liver segmentation in MRI remains a challenging task due to the high variability in liver morphology and the limited availability of high-quality annotated datasets. To address these challenges, this study presents an advanced semi-supervised learning framework that integrates cross-teaching with pseudo-label generation and intra-batch entropy minimization.
View Article and Find Full Text PDFEur J Gastroenterol Hepatol
September 2025
Background: Prior studies have implicated diabetes as a risk factor for pancreatic cancer, yet the impact of diabetes progression on pancreatic cancer incidence remains unclear. We aim to assess pancreatic cancer risk across different stages of diabetes.
Methods: Employing a predefined search strategy, we conducted a literature review of electronic databases up to 29 February 2024.