Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Fractures are a significant global public health concern, imposing a substantial economic burden, particularly among the elderly. However, research on the fracture burden in Asia remains limited, highlighting the need for comprehensive and up-to-date studies to support the effective planning and allocation of healthcare resources across the region.
Methods: Using the Global Burden of Disease (GBD) 2021 database, we analyzed the age-standardized rates (ASRs) of incidence (ASIR), prevalence (ASPR), and years lived with disability (YLDs) (ASYR) associated with fracture burden across Asia. Our study explored trends over time, variations by age, sex, and country, and examined the correlation between fracture burden and the sociodemographic index (SDI).
Results: In 2021, fractures in Asia caused 91.3 million (95 % uncertainty interval, 83.65-99.47) incident cases, 232.71 million (95 % UI, (215.57-250.39) prevalent cases, and 12.97 million (95 % UI, 8.89-17.82) YLDs, with age-standardized rates of 1968.49 (95 % UI, 1799.15-2147.14) for incidence (ASIR), 4683.96 (95 % UI, 4347.58-5036.61) for prevalence (ASPR), and 261.72 (95 % UI, 179.43-358.94) for YLDs (ASYR) per 100,000 population. Despite a higher absolute burden, Asian age-standardized rates of fracture were slightly lower than the global average. For ASYR, the most burdensome fractures were those of the patella, tibia/fibula/ankle, hip, and pelvis. Between 1990 and 2021, fracture incident cases, prevalent cases, and YLDs in Asia increased markedly. Age and sex differences were observed, with the elderly experiencing the highest fracture burden, particularly for hip fractures in women. While men had a higher overall fracture burden, women faced a greater fracture disease burden in the elderly population. Geographically, High-income Asia Pacific and Central Asia exhibited the highest age-standardized YLD rates, while South and East Asia had the largest number of fractures and YLDs.
Conclusions: Our study provides an in-depth analysis of the fracture burden in Asia. From 1990 to 2021, the overall age-standardized fracture burden in Asia showed a gradual decline, yet the burden of hip fractures continued to increase. Asia holds the highest absolute number of fracture burden globally, with East Asia and South Asia being the primary regions contributing to this burden. The fracture burden increases with age in Asia, and women experience a higher fracture burden than men in older age groups. Strengthening surveillance and targeted prevention is essential to reduce the future fracture burden.
The Translational Potential Of This Article: Fracture is a kind of health problem with high incidence and serious disease burden in Asia. Although overall burden of disease for fractures in Asia from 1990 to 2021 was decreasing, the burden of hip fracture disease in Asia has continued to rise from 1990 to 2021 in terms of incidence and prevalence. Males had a higher fracture burden than females in Asia, yet females had a higher fracture disease burden in the elderly population in 2021.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12140854 | PMC |
| http://dx.doi.org/10.1016/j.jot.2025.04.001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Background: Pressure injuries are common, difficult to manage, and carry a high economic burden. They are challenging to physicians and a burden to society.
Case Report: An 89-year-old male, who had previously undergone internal fixation with screws and rods for a right intertrochanteric fracture, developed a deep circular open ulcer measuring 11 cm × 7.
Preclinical validation of finite element models for predicting in vivo residual plate bending using continuous implant sensor data.
J Orthop Translat
November 2025
AO Research Institute Davos, Davos, Switzerland.
Background/objective: Plate failure, including bending, is a critical issue in orthopedic fracture fixation, with clinical failure rates of 3.5%-19%, burdening patients and healthcare systems. Preclinical ovine models have observed similar plate bending due to overloading.
View Article and Find Full Text PDFIntroducing surgical workflow recognition in orthopaedic surgery with timestamp supervision.
Comput Biol Med
September 2025
University of Strasbourg, CNRS, INSERM, ICube, UMR7357, 300 boulevard Sébastien Brant, Illkirch, 67412, France. Electronic address:
Surgical workflow recognition (SWR) is associated with numerous potential applications to improve patient safety and surgeon performance. So far, SWR studies have mainly focused on endoscopic procedures due to the scarcity of publicly available open surgery video datasets. In this article, we propose for the first time to work on an open orthopaedic surgery called minimally invasive plate osteosynthesis (MIPO) for distal radius fractures (DRFs).
View Article and Find Full Text PDFEconomic burden and cost-effectiveness of treatments for open tibia fractures in Malawi: Economic analysis of a multicentre prospective cohort study.
PLoS One
September 2025
University of Glasgow, Glasgow, United Kingdom.
Background: Open tibia fractures result in substantial lifelong disability for patients, and are expensive to treat. As the injury typically affects young working men, the societal costs from open tibia fractures are likely to also be high in low income countries, but remain largely unknown. We therefore investigated the overall societal costs and cost-effectiveness of different orthopaedic treatments at one year following an open tibia fracture in Malawi.
View Article and Find Full Text PDFIn Reference to Cost and Inpatient Burden of Mandible Fracture Management: A 14-Year Analysis.
Laryngoscope
September 2025
School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.