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: Various forms of head and neck cancer (HNC) surgery that include a neck dissection procedure have been shown to negatively influence the neuromusculoskeletal function of the structures affected. This review aimed to identify the neuromusculoskeletal impairments experienced by individuals with HNC following surgery involving different types of neck dissection procedures. The search was conducted in four databases, encompassing randomized control trials (RCTs), cross-sectional studies, and cohort studies that explored neuromusculoskeletal impairments and dysfunction following HNC surgery. The risk of bias in the included studies was assessed using the ROB 2 tool for RCTs and the ROBINS-I tool for non-RCTs. Sixty-seven studies were included (prospective cohort studies = 29; cross-sectional studies = 21; retrospective studies = 13; and RCTs = 4). This review revealed diverse neuromusculoskeletal impairments and disabilities in individuals with HNC after undergoing various types of neck dissection. The overall quality of evidence was low due to methodological limitations and variability in assessment tools. : The extent and type of neuromusculoskeletal impairment resulting from surgery varied depending on the type of surgery and the outcome measures used. Further high-quality studies with standardized assessment, consistent outcome measures, and long-term follow-up are needed to improve the credibility of research in this area.
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http://dx.doi.org/10.3390/life15050800 | DOI Listing |
J Cancer Surviv
September 2025
Department of Otolaryngology - Head and Neck Surgery, University of Pittsburgh Medical Center, 203 Lothrop St # 500, Pittsburgh, PA, 15213, USA.
Purpose: Despite its importance, little is known about the patterns and predictors of Survivorship Clinic attendance in head and neck cancer (HNC). We sought to determine the cumulative incidence of Survivorship Clinic attendance stratified by demographic, clinical, and socioeconomic factors, and to identify factors independently associated with attendance.
Methods: Our analysis population consisted of 2,252 patients diagnosed with primary HNC and seen at our institution's HNC Survivorship Clinic after completing treatment from 2016-2021.
Disabil Rehabil
September 2025
Department of Rehabilitation Sciences and Physiotherapy, University of Leuven, Leuven, Belgium.
Purpose: This study aims to cross-culturally validate the Dutch version of the Lymphedema Symptom Intensity and Distress Survey-Head and Neck version 2.0 (LSIDS-H&N v2.0).
View Article and Find Full Text PDFLaryngoscope
September 2025
Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, California, USA.
Objective: To evaluate and quantify the mediation effects of neighborhood socioeconomic status (SES), insurance status, and quality of care on racial disparities in HNC survival.
Methods: Retrospective cohort study of data from the California Cancer Registry dataset linked with discharge records and hospital characteristics from the California Department of Health Care Access and Information. The study cohort included adult patients with HNC diagnosed between January 1, 2010, and December 31, 2019.
Int J Mol Med
November 2025
The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu 730000, P.R. China.
Head and neck cancer (HNC) is a common malignant disease in otorhinolaryngology; however, its pathogenesis remains to be fully elucidated. Currently, the treatment for HNC mainly comprises surgery assisted by other methods, including radiotherapy, chemotherapy and immunotherapy. After surgical treatment, the laryngeal function, and swallowing and breathing abilities of patients can be affected to a certain extent, and the loss of vocal ability can cause daily communication obstacles and affect the physical and mental health of patients.
View Article and Find Full Text PDFOral Oncol
September 2025
Center for Surgery and Public Health, Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA; Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Division of Otolaryngology-Head and Neck Surgery, Brigham and Women's Hospital; Center for Head and Neck Oncology, D
Introduction: Delays in head and neck cancer (HNC) diagnosis and treatment and financial burdens of care are often rooted in social determinants of health (SDOH), such as financial instability, socioeconomic status (SES), health insurance status, and transportation barriers. While these factors are well recognized, their underlying impact on access to care remains underexplored; this qualitative study aims to investigate how these SDOH facilitate or hinder HNC care through insights from patients and healthcare workers (HCWs) in the United States, to identify targets for intervention.
Methods: Semi-structured interviews were conducted with patients with newly diagnosed HNC, and HCWs caring for these patients, between June 2022 and July 2023.