Monoterpenoids and iridoids isolated from Gardenia jasminoides.

Fitoterapia

School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China; The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou 450046, China; Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases Co-Construction by Henan

Published: July 2025


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Article Abstract

Seven monoterpenoids (1-7) and thirteen iridoids (8-20), including one undescribed monoterpenoids (1) and five undescribed iridoids (8, 11, 16, 19, and 20) were isolated from Gardenia jasminoides Ellis. The structures of the compounds were determined by extensive spectroscopic data analysis, DP4+ analysis and comparing the calculated electronic circular dichroism (ECD) spectra with the experimental ECD spectra. All compounds were evaluated for their acetylcholinesterase and α-glucosidase inhibitory effects whose results showed that all compounds exhibited slightly inhibitory activities.

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http://dx.doi.org/10.1016/j.fitote.2025.106632DOI Listing

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